Operating Income
Gross Profit
Vertex Pharmaceuticals Gross Profit increased by 2.3% to $2.72B in Q4 2025 compared to the prior quarter. Year-over-year, this metric grew by 9.5%, from $2.49B to $2.72B. Over 4 years (FY 2021 to FY 2025), Gross Profit shows an upward trend with a 11.6% CAGR. This is a positive signal — higher values indicate stronger performance for this metric.
Analysis
StatementIncome Statement
SectionOperating Income
CategoryProfitability
SignalHigher is better
VolatilityStable
First reportedQ1 2013
Last reportedQ1 2026
How to read this metric
Higher gross profit indicates a strong ability to command premium pricing and manage production costs effectively.
Detailed definition
The profit a company makes after deducting the costs associated with making and selling its products, or the costs assoc...
Peer comparison
Premium hardware brands aim for higher gross profit margins than commodity electronics manufacturers.
Metric ID:
is_gross_profitHistorical Data
19 periods
| Q2 '21 | Q3 '21 | Q4 '21 | Q1 '22 | Q2 '22 | Q3 '22 | Q4 '22 | Q1 '23 | Q2 '23 | Q3 '23 | Q4 '23 | Q1 '24 | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Value | $1.57B | $1.75B | $1.83B | $1.85B | $1.93B | $2.04B | $2.02B | $2.11B | $2.18B | $2.16B | $2.15B | $2.35B | $2.27B | $2.38B | $2.49B | $2.41B | $2.56B | $2.66B | $2.72B |
| QoQ Change | — | +11.6% | +4.4% | +1.5% | +4.5% | +5.7% | -1.2% | +4.4% | +3.6% | -0.9% | -0.7% | +9.2% | -3.2% | +4.6% | +4.6% | -3.3% | +6.2% | +4.1% | +2.3% |
| YoY Change | — | — | — | — | +23.6% | +17.0% | +10.6% | +13.8% | +12.9% | +5.9% | +6.5% | +11.4% | +4.1% | +9.9% | +15.8% | +2.5% | +12.5% | +11.9% | +9.5% |
Range$1.57B – $2.72B
CAGR+13.1%
Avg YoY Growth+11.2%
Median YoY Growth+11.4%
Current Streak3 quarters growth
Gross Profit at Other Companies
Frequently Asked Questions
- What is Vertex Pharmaceuticals's gross profit?
- Vertex Pharmaceuticals (VRTX) reported gross profit of $2.72B in Q4 2025.
- How has Vertex Pharmaceuticals's gross profit changed year-over-year?
- Vertex Pharmaceuticals's gross profit increased by 9.5% year-over-year, from $2.49B to $2.72B.
- What is the long-term trend for Vertex Pharmaceuticals's gross profit?
- Over 4 years (2021 to 2025), Vertex Pharmaceuticals's gross profit has grown at a 11.6% compound annual growth rate (CAGR), from $6.67B to $10.35B.
- What does gross profit mean?
- The money left over from sales after paying for the direct cost of goods sold.