Income StatementBalance SheetCash FlowSegments
Alnylam Pharmaceuticals logo

Alnylam Pharmaceuticals Income Statement

Revenue, expenses, and profitability over time

Alnylam Pharmaceuticals generated $4.3B in trailing twelve-month revenue, up 0.8% year-over-year. Net income was $538.0M with a 12.55% net margin. Gross margin stands at 81.0% and operating margin at 17.54%. Diluted EPS is $3.98, which grew 3.2% year-over-year. Based on the Q1 2026 filing.

Total Revenue (TTM)$4.3BGross Profit (TTM)$3.5BOperating Income (TTM)$752.1MNet Income (TTM)$538.0MEps Diluted (TTM)$3.98
Latest FilingQ1 2026
Report Date2026-04-30
Market Cap$39.2B
P/E Ratio72.83
ROE71.66%

Operating Expenses

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Stock-Based Compensation Expense$91.6M$56.7M$111.7M$108.2M$71.6M$70.2M
Share-Based Compensation Expense$91.6M$56.7M$111.7M$108.2M$71.6M$70.2M
Other Segment Items-$80.8M$9.2M-$6.4M-$74.2M$76.6M-$4.3M
Stock-based compensation expense$91.6M$56.7M$111.7M$108.2M$71.6M$70.2M
Cost of collaborations and royalties$168.0K$858.0K$924.0K$2.9M$0.0$3.6M
Research and development$300.2M$265.1M$323.6M$358.8M$372.2M$364.9M
Selling, general and administrative$295.3M$239.9M$323.3M$322.1M$325.4M$322.6M
Share-Based Compensation$91.6M$56.7M$111.7M$108.2M$71.6M$70.2M
Total operating expenses$698.3M$576.1M$789.9M$881.0M$965.3M$898.5M

Other

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Capital Expenditures$9.1M$9.0M$14.3M$12.1M$23.3M$21.8M
Change in Accounts Receivable$59.5M$7.4M$136.9M$399.9M—$110.4M
Change in Deferred Revenue-$12.8M-$27.3M-$13.1M-$12.5M$0.0-$1.6M
OCI Unrealized Holding Gain (Loss) on Securities, Net of Tax-$4.8M$1.0M-$343.0K$1.1M$0.0-$3.7M
Unrealized Gain (Loss) on Securities-$4.8M$1.0M-$343.0K$1.1M$0.0-$3.7M
Income Taxes Paid, Net$6.2M$3.0M-$1.9M$1.3M—$2.4M
Interest Paid, Net$12.3M$68.9M$12.6M$23.9M$113.3M$64.2M
OCI Unrealized Holding Gain (Loss) on Securities, Net of Tax-$4.8M$1.0M-$343.0K$1.1M$0.0-$3.7M
Capital investments accrued but not yet paid$1.6M$3.7M$431.0K$5.5M$1.3M$9.2M
Comprehensive Income (Loss), Net of Tax, Attributable to Parent-$93.5M-$21.3M-$58.7M$259.3M$148.9M$201.2M
Deferred taxes-$107.4M$9.6M$9.7M$5.6M-$27.2M$9.3M
Depreciation, Amortization and Accretion, Net$14.2M$14.4M$13.9M$13.8M$13.5M$13.6M
Income Taxes Paid, Net$6.2M$3.0M-$1.9M$1.3M—$2.4M
Increase (Decrease) in Accounts Receivable$59.5M$7.4M$136.9M$399.9M—$110.4M
Increase (decrease) in contract liabilities and current deferred income-$12.8M-$27.3M-$13.1M-$12.5M$0.0-$1.6M
Increase (Decrease) in Inventories-$849.0K-$6.2M-$11.1M-$5.0M—$3.3M
Increase (Decrease) in Prepaid Expense and Other Assets-$25.3M$32.8M-$6.8M$20.7M$71.0M$6.3M
Interest Expense Nonoperating$39.0M$58.3M$40.2M$44.4M$109.7M$69.3M
Interest Paid, Excluding Capitalized Interest, Operating Activity$12.3M$68.9M$12.6M$23.9M$113.3M$64.2M
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation$31.0M$46.1M$51.8M-$448.3M—$15.7M
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation-$52.9M$113.8M-$141.4M$501.1M$0.0-$25.5M
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation-$94.7M-$120.3M$155.7M$325.1M$163.6M$70.5M
Net unrealized gains (losses) on securities still held-$4.8M$1.0M-$343.0K$1.1M$0.0-$3.7M
Other income, net (Note 6)-$80.8M$9.2M-$6.4M-$74.2M$76.6M-$4.3M
All other operating activities-$6.8M-$19.4M-$18.5M$6.4M$0.0$3.0M
Payments to Acquire Debt Securities, Available-for-Sale$486.7M$401.6M$459.6M$208.0M$235.9M$261.6M
Payments to Acquire Property, Plant, and Equipment$9.1M$9.0M$14.3M$12.1M$23.3M$21.8M
Payments to Acquire Restricted Investments$0.0$48.8M$9.3M$1.7M$0.0$4.1M
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options$36.3M$49.4M$81.2M$77.7M$41.7M$13.2M
Revenue From Contract With Customer Excluding Assessed Tax$593.2M$594.2M$773.7M$1.2B$1.1B$1.2B
Stock-based compensation$91.6M$56.7M$111.7M$108.2M$71.6M$70.2M
Other Comprehensive Income (Loss)-$93.5M-$21.3M-$58.7M$259.3M$148.9M$201.2M

Tax

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Cash Paid for Income Taxes$6.2M$3.0M-$1.9M$1.3M—$2.4M
Income Taxes Paid, Net$6.2M$3.0M-$1.9M$1.3M—$2.4M
Income tax expense-$110.2M$15.9M$30.9M-$12.1M—$15.7M
Income Taxes Paid, Net$6.2M$3.0M-$1.9M$1.3M—$2.4M
Income and Other Taxes$6.2M$3.0M-$1.9M$1.3M—$2.4M

Other Income & Expense

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Cash Paid for Interest$12.3M$68.9M$12.6M$23.9M$113.3M$64.2M
Equity Securities FV-NI Gain (Loss)-$166.0K-$956.0K-$1.4M$0.0$0.0$0.0
Gain (Loss) on Cenovus Energy Investment-$166.0K-$956.0K-$1.4M$0.0$0.0$0.0
Other Charges-$80.8M$9.2M-$6.4M-$74.2M$76.6M-$4.3M
Gains (losses) on equity investments-$166.0K-$956.0K-$1.4M$0.0$0.0$0.0
Interest expense$39.0M$58.3M$40.2M$44.4M$109.7M$69.3M
Interest income$31.0M$28.7M$27.5M$28.7M$26.6M$26.6M
Other income (expense), net-$88.8M-$20.4M-$19.2M-$129.0M-$9.8M-$47.0M
Net gains (losses) on equity securities-$166.0K-$956.0K-$1.4M$0.0$0.0$0.0

Earnings Per Share

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Basic earnings per share$-0.66$-0.14$-0.51$1.91$1.13$1.55
Diluted earnings per share$-0.66$-0.14$-0.51$1.84$1.14$1.51
Weighted-average shares, basic—129.7M130.6M131.4M—132.9M
Weighted-average shares, diluted—129.7M130.6M137.3M—138.2M

Operating Income

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Gross profit$490.5M$524.0M$631.7M$1.1B$829.3M$959.7M
Operating income-$105.2M$18.1M-$16.2M$368.0M$131.7M$268.6M

Income Before Tax

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Income before income taxes-$194.0M-$2.4M-$35.4M$239.0M$121.9M$221.7M

Net Income

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Net income-$83.8M-$18.3M-$66.3M$251.1M$147.2M$206.0M

Cost of Revenue

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Total cost of revenue$102.6M$70.2M$142.0M$197.2M$267.7M$207.5M

Revenue

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Total revenue$593.2M$594.2M$773.7M$1.2B$1.1B$1.2B