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Agios Pharmaceuticals AGIO Return on invested capital

Return on invested capital at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
13%+4.2pp
Pfizer logo
PfizerPFE
6%
Vertex Pharmaceuticals logo
Vertex PharmaceuticalsVRTX
26.8%+23.0pp
Incyte logo
IncyteINCY
65.6%+61.0pp
BioMarin Pharmaceuticals logo
BioMarin PharmaceuticalsBMRN
5.2%-3.3pp
Disc Medicine logo
Disc MedicineIRON
-44.3%

Other financials

Income statement

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Revenue$20.7M+138%
Gross profit$19.4M+154%
Operating income-$110.0M-3.2%
Net income-$99.1M-11.0%
EPS (diluted)-$1.69-9.0%

Balance sheet

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Cash & equivalents$113.6M+43.9%
Total debt$35.7M-32.5%
Total equity$1.1B-24.4%
Total assets$1.2B-23.8%

Cash flow

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Operating cash flow-$118.9M-6.7%
CapEx$769.0K+0.4%
Free cash flow-$119.7M-6.6%

Valuation

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Market cap$2.12B+18.1%
Enterprise value$2.04B+15.2%
P/S32.1×-16.4×

Profitability

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Gross margin90%+2.5pp
Operating margin-720%-204pp
Net margin-639.8%
FCF margin-582.5%-185pp

Returns & leverage

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Return on equity-32.8%
Debt / equity0.0×
Current ratio14.2×-4.3×

Where this comes from

Calculated from Agios Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The official record: Agios Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Agios Pharmaceuticals's return on invested capital?
Agios Pharmaceuticals (AGIO) reported return on invested capital of -38.5% in Q1 2026.
How has Agios Pharmaceuticals's return on invested capital changed year-over-year?
Agios Pharmaceuticals's return on invested capital increased by 6.8% year-over-year, from -41.3% to -38.5%.
What is the long-term trend for Agios Pharmaceuticals's return on invested capital?
Over 5 years (2020 to 2025), Agios Pharmaceuticals's return on invested capital has grown at a -11.5% compound annual growth rate (CAGR), from -65.3% to -35.4%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.