What are CareDx's profit margins?

CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.

Where do CareDx's ratios come from?

Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

CareDx CDNA Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Operating margin	-3.9%-18.3pp	-8.1%-20.3pp	16.7%+69.8pp	13.5%+74.6pp	14.4%+87.7pp
Net margin	-2%-19.9pp	-5.6%-21.4pp	19.7%+68.7pp	17.1%+73.0pp	17.9%+85.7pp
EBITDA margin	-0.2%-18.7pp	-4.2%-20.6pp	20.7%+69.2pp	17.7%+73.8pp	18.5%+86.4pp
Returns
Return on equity	-2.4%-21.9pp	-6.3%-22.7pp	24.1%+70.0pp	19.6%+69.2pp	19.5%+74.7pp
Return on assets	-1.8%-15.0pp	-4.7%-15.7pp	15.5%+46.8pp	12.8%+46.6pp	13.2%+51.2pp
Return on invested capital	-5.6%-24.8pp	-11.1%-27.2pp	26.2%+85.6pp	18.8%+84.4pp	19.2%+89.0pp
Efficiency
Asset turnover	0.9×+0.2×	0.8×+0.1×	0.8×+0.1×	0.7×+0.1×	0.7×+0.2×
Liquidity
Current ratio	3.4×-0.7×	2.9×-1.1×	3×-1.1×	3.3×-0.8×	4.1×-0.2×
Quick ratio	3.1×-0.8×	2.6×-1.2×	2.7×-1.1×	3×-0.8×	3.8×-0.2×
Cash ratio	1×-0.1×	0.7×-0.6×	0.9×-0.3×	0.7×-0.5×	1×-0.3×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Debt-to-assets	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Interest coverage	-2×-6.2×	-3.4×-6.8×	5.8×+19.8×	4.1×+19.2×	4.3×+21.0×
Per Share
Book value per share	$5.90-14.0%	$5.69-14.9%	$5.79+12.1%	$6.03+18.9%	$6.86+38.5%
Valuation
Market capitalization	$1.4B+32.2%	$968.99M-15.6%	$773.92M-53.0%	$1.05B+29.7%	$983.81M+79.4%
Enterprise value	$1.35B+34.6%	$929.2M-12.5%	$709.58M-55.1%	$1.01B+35.7%	$924.79M+89.7%
Price / sales	3.4×+0.3×	2.6×-0.9×	2.2×-3.1×	3.1×+0.4×	2.8×+0.8×
Price / book	4.5×+1.7×	3.2×+0.2×	2.5×-3.5×	3.2×+0.1×	2.6×+0.5×
EV / sales	3.3×+0.4×	2.4×-0.7×	2×-3.1×	3×+0.5×	2.7×+0.9×
Earnings yield	-0.6%-6.4pp	-2.2%-6.8pp	9.1%+18.4pp	5.5%+26.0pp	6.3%+40.3pp

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Questions, answered.

What are CareDx's profit margins?: CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.
Where do CareDx's ratios come from?: Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.