What are CareDx's profit margins?

CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.

Where do CareDx's ratios come from?

Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

CareDx CDNA Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Operating margin	-3.9%-18.3pp	-8.1%-20.3pp	16.7%+69.8pp	13.5%+74.6pp	14.4%+87.7pp
Net margin	-2%-19.9pp	-5.6%-21.4pp	19.7%+68.7pp	17.1%+73.0pp	17.9%+85.7pp
Returns
Return on equity	-2.4%-21.9pp	-6.3%-22.7pp	24.1%+70.0pp	19.6%+69.2pp	19.5%+74.7pp
Return on invested capital	-5.6%-24.8pp	-11.1%-27.2pp	26.2%+85.6pp	18.8%+84.4pp	19.2%+89.0pp
Efficiency
Asset turnover	0.9×+0.2×	0.8×+0.1×	0.8×+0.1×	0.7×+0.1×	0.7×+0.2×
Liquidity
Current ratio	3.4×-0.7×	2.9×-1.1×	3×-1.1×	3.3×-0.8×	4.1×-0.2×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Per Share
Book value per share	$5.90-14.0%	$5.69-14.9%	$5.79+12.1%	$6.03+18.9%	$6.86+38.5%
Valuation
Market capitalization	$1.4B+32.2%	$968.99M-15.6%	$773.92M-53.0%	$1.05B+29.7%	$983.81M+79.4%
Price / sales	3.4×+0.3×	2.6×-0.9×	2.2×-3.1×	3.1×+0.4×	2.8×+0.8×
Price / book	4.5×+1.7×	3.2×+0.2×	2.5×-3.5×	3.2×+0.1×	2.6×+0.5×

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Questions, answered.

What are CareDx's profit margins?: CareDx (CDNA) runs a 65.5% gross margin and a -3.9% operating margin, with a -2.0% net margin.
Where do CareDx's ratios come from?: Every ratio is computed from CareDx's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.