What are Crinetics Pharmaceuticals's profit margins?

Crinetics Pharmaceuticals (CRNX) runs a 150.0% gross margin and a -3020.3% operating margin, with a -2747.2% net margin.

Where do Crinetics Pharmaceuticals's ratios come from?

Every ratio is computed from Crinetics Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Crinetics Pharmaceuticals CRNX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Operating margin	-3,020.3%+46,549pp	-6,714.8%+25,899pp	-31,130.2%-1,605pp	-30,392.2%-10,324pp	-49,569.7%-36,998pp
Net margin	-2,747.2%+40,444pp	-6,046.2%+22,674pp	-27,563.3%-815pp	-26,568.5%-7,901pp	-43,191.1%-31,263pp
EBITDA margin	-2,997.5%+46,146pp	-6,664.2%+25,681pp	-30,890.2%-1,582pp	-30,144.9%-10,204pp	-49,143.9%-36,638pp
Free cash flow margin	-2,321.7%+33,144pp	-4,985.5%+17,540pp	-23,337.1%-3,330pp	-22,269.8%-8,597pp	-35,465.9%-26,006pp
Returns
Return on equity	-39.2%-8.3pp	-40.2%-8.1pp	-44.4%-4.2pp	-36.9%+10.7pp	-30.8%+9.9pp
Return on assets	-35.9%-7.9pp	-36.3%-7.5pp	-39.7%-4.5pp	-33.2%+8.8pp	-28.1%+8.4pp
Return on invested capital	-45.1%-1.8pp	-50.4%-9.3pp	-60.6%-0.7pp	-48.4%+21.2pp	-43.3%+20.9pp
Efficiency
Asset turnover	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Liquidity
Current ratio	18.6×-3.9×	12.3×-10.7×	15.1×-1.3×	17.8×+1.7×	22.5×+4.8×
Quick ratio	18.6×-4.0×	12.3×-10.7×	15.1×-1.3×	17.8×+1.7×	22.5×+4.8×
Cash ratio	1.6×-0.1×	1.2×-3.3×	1.5×-4.4×	0.8×-4.8×	1.7×-6.0×
Leverage
Debt-to-equity	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Debt-to-assets	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Per Share
Book value per share	$12.30-8.7%	$10.55-35.7%	$11.38+9.4%	$12.49+18.8%	$13.47+11.3%
Valuation
Market capitalization	$3.8B+21.9%	$4.42B-6.8%	$3.92B-4.1%	$2.9B-17.9%	$3.12B-14.4%
Enterprise value	$3.74B+21.5%	$4.36B-3.6%	$3.86B+0.9%	$2.89B-11.8%	$3.08B-6.9%
Price / sales	210.5×-3,896×	574×-3,990×	2,555.3×-1,381×	2,082.2×-468×	4,106.4×+2,258×
Price / book	3×+0.5×	4.5×+0.9×	3.7×-1.3×	2.5×-1.8×	2.5×-1.7×
EV / sales	206.7×-3,840×	567×-3,791×	2,514.2×-1,166×	2,079.5×-291×	4,047.1×+2,373×
Free cash flow yield	-11%-2.4pp	-8.7%-3.8pp	-9.1%-4.0pp	-10.7%-5.3pp	-8.6%-3.5pp
Earnings yield	-13.1%-2.5pp	-10.5%-4.2pp	-10.8%-4.0pp	-12.8%-5.4pp	-10.5%-4.1pp

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Questions, answered.

What are Crinetics Pharmaceuticals's profit margins?: Crinetics Pharmaceuticals (CRNX) runs a 150.0% gross margin and a -3020.3% operating margin, with a -2747.2% net margin.
Where do Crinetics Pharmaceuticals's ratios come from?: Every ratio is computed from Crinetics Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.