What are Crinetics Pharmaceuticals's profit margins?

Crinetics Pharmaceuticals (CRNX) runs a 150.0% gross margin and a -3020.3% operating margin, with a -2747.2% net margin.

Where do Crinetics Pharmaceuticals's ratios come from?

Every ratio is computed from Crinetics Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Crinetics Pharmaceuticals CRNX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Operating margin	-3,020.3%+46,549pp	-6,714.8%+25,899pp	-31,130.2%-1,605pp	-30,392.2%-10,324pp	-49,569.7%-36,998pp
Net margin	-2,747.2%+40,444pp	-6,046.2%+22,674pp	-27,563.3%-815pp	-26,568.5%-7,901pp	-43,191.1%-31,263pp
Returns
Return on equity	-39.2%-8.3pp	-40.2%-8.1pp	-44.4%-4.2pp	-36.9%+10.7pp	-30.8%+9.9pp
Return on invested capital	-45.1%-1.8pp	-50.4%-9.3pp	-60.6%-0.7pp	-48.4%+21.2pp	-43.3%+20.9pp
Efficiency
Asset turnover	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Liquidity
Current ratio	18.6×-3.9×	12.3×-10.7×	15.1×-1.3×	17.8×+1.7×	22.5×+4.8×
Leverage
Debt-to-equity	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Per Share
Book value per share	$12.30-8.7%	$10.55-35.7%	$11.38+9.4%	$12.49+18.8%	$13.47+11.3%
Valuation
Market capitalization	$3.8B+21.9%	$4.42B-6.8%	$3.92B-4.1%	$2.9B-17.9%	$3.12B-14.4%
Price / sales	210.5×-3,896×	574×-3,990×	2,555.3×-1,381×	2,082.2×-468×	4,106.4×+2,258×
Price / book	3×+0.5×	4.5×+0.9×	3.7×-1.3×	2.5×-1.8×	2.5×-1.7×

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Questions, answered.

What are Crinetics Pharmaceuticals's profit margins?: Crinetics Pharmaceuticals (CRNX) runs a 150.0% gross margin and a -3020.3% operating margin, with a -2747.2% net margin.
Where do Crinetics Pharmaceuticals's ratios come from?: Every ratio is computed from Crinetics Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.