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CRISPR Therapeutics CRSP Ratios & Valuation

TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
Profitability
Operating margin-15,754.2%-18,933.6%-1,498.3%
Net margin-13,856.5%-16,569.8%-1,273.7%
EBITDA margin-15,289.6%-18,378.7%-1,449.6%
Free cash flow margin-9,777.6%-8,960pp-9,855.5%-9,468pp-790.7%-696pp-855.6%-793pp-817.1%-756pp
Returns
Return on equity-31.2%-30.2%-25.3%
Return on assets-23.2%-25.8%-21.7%
Return on invested capital-32.4%-36.5%-30.4%
Efficiency
Asset turnover0.0×0.0×-0.1×-0.1×-0.1×
Liquidity
Current ratio18×+2.3×13.3×-8.8×16.2×-5.4×16.6×+0.9×15.6×-2.2×
Quick ratio18×+2.3×13.3×-8.8×16.2×-5.4×16.6×+0.9×15.6×-2.2×
Cash ratio3.1×+1.1×2.3×-1.1×2.4×-0.1×1.9×-1.9×-4.0×
Leverage
Debt-to-equity0.4×+0.3×0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×
Debt-to-assets0.3×+0.2×0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×
Per Share
Book value per share$18.89-11.2%$21.37-6.7%$20.98-7.8%$19.65-15.8%$21.28-16.5%
Valuation
Market capitalization$4.57B+56.4%$5B+48.8%$5.89B+47.3%$4.04B-11.9%$2.92B-46.7%
Enterprise value$4.93B+69.8%$4.86B+47.8%$5.82B+45.4%$4.06B-6.3%$2.9B-41.9%
Price / sales1,112.8×+1,035×1,423.8×+1,334×153.8×+134×106.2×+83.5×77.5×+57.3×
Price / book2.5×+0.9×2.6×+0.9×3.1×+1.0×2.4×0.0×1.6×-1.0×
EV / sales1,201.6×+1,125×1,383.7×+1,296×151.8×+132×106.8×+85.3×77.1×+58.7×
Free cash flow yield-8.8%+1.8pp-6.9%-2.6pp-5.1%-0.4pp-8.1%-5.3pp-10.5%-7.5pp
Earnings yield-12.5%-11.6%-8.3%

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Questions, answered.

Where do CRISPR Therapeutics's ratios come from?
Every ratio is computed from CRISPR Therapeutics's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.