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Denali Therapeutics Inc. DNLI Business Segments — Operating Expenses

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Other financials

Income statement

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Revenue-
Operating income-$137.4M+5.6%
Net income-$128.4M+3.4%
EPS (diluted)-$0.69+11.5%

Balance sheet

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Cash & equivalents$390.7M+551%
Total debt$40.0M-22.3%
Total equity$926.1M-17.5%
Total assets$1.3B-0.4%

Cash flow

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Operating cash flow-$131.2M+0.2%
CapEx$2.5M-51.4%
Free cash flow-$133.7M+2.1%

Valuation

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Market cap$3.93B+54.2%

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-49.6%+34.2pp
Debt / equity0.0×
Current ratio9.3×-0.3×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:OperatingExpenses.

The official record: Denali Therapeutics Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s business segments — operating expenses?
Denali Therapeutics Inc. (DNLI) reported business segments — operating expenses of $137.36M in Q1 2026.
How has Denali Therapeutics Inc.'s business segments — operating expenses changed year-over-year?
Denali Therapeutics Inc.'s business segments — operating expenses decreased by 5.6% year-over-year, from $145.58M to $137.36M.
What is the long-term trend for Denali Therapeutics Inc.'s business segments — operating expenses?
Over 3 years (2022 to 2025), Denali Therapeutics Inc.'s business segments — operating expenses has grown at a 7.3% compound annual growth rate (CAGR), from $449.21M to $555.34M.
What does business segments — operating expenses mean?
The sum of all research, development, and administrative costs incurred during the period. This metric represents the total cash outflow required to sustain the company's operations before accounting for revenue or financing activities. It is a critical measure for evaluating the company's overall operational scale and cash burn.