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Denali Therapeutics Inc. DNLI Total Operating Expenses

Discontinued — last reported Q1 '26

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Segments

By segment

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Therapeutics Segment$134.15M-0.6%

Other financials

Income statement

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Revenue$3.6M
Gross profit$3.5M
Operating income-$130.5M+3.3%
Net income-$127.6M-2.8%
EPS (diluted)-$0.68+5.6%

Balance sheet

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Cash & equivalents$204.6M+41.8%
Total debt$37.7M-21.4%
Total equity$835.2M-18.7%
Total assets$1.2B-0.7%

Cash flow

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Operating cash flow-$97.0M-28.8%
CapEx$805.0K-81.2%
Free cash flow-$97.8M-22.9%

Valuation

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Market cap$3.92B+88.3%
Enterprise value$3.76B+89.0%
P/S1,089×+1,084×

Profitability

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Operating margin-37,938%-37,986pp
Net margin-33,121.9%-33,159pp
FCF margin-31,736.3%-31,830pp

Returns & leverage

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Return on equity-54.9%+34.3pp
Debt / equity0.0×
Current ratio8.4×-1.9×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:OperatingExpenses.

The source filing: Denali Therapeutics Inc.’s 10-Q, filed May 7, 2026.

Filed
May 7, 2026, 4:12 PM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001714899-26-000064
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
Operating expenses:
Research and development$103,846$116,227
General and administration33,51129,353
Total operating expenses137,357145,580
Loss from operations(137,357)(145,580)
Interest and other income, net8,91012,610
Net loss$(128,447)$(132,970)
Other comprehensive income (loss):

Item 1. Financial Statements (Unaudited)

FAQ

What is Denali Therapeutics Inc.'s total operating expenses?
Denali Therapeutics Inc. (DNLI) reported total operating expenses of $137.36M in Q1 2026.
How has Denali Therapeutics Inc.'s total operating expenses changed year-over-year?
Denali Therapeutics Inc.'s total operating expenses decreased by 5.6% year-over-year, from $145.58M to $137.36M.
What is the long-term trend for Denali Therapeutics Inc.'s total operating expenses?
Over 4 years (2021 to 2025), Denali Therapeutics Inc.'s total operating expenses has grown at a 12.7% compound annual growth rate (CAGR), from $344.41M to $555.34M.
What does total operating expenses mean?
The sum of all operating costs including COGS, SG&A, R&D, D&A, and other operating charges. Revenue minus total operating expenses equals operating income.

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