What are Illumina's profit margins?

Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.

Where do Illumina's ratios come from?

Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Illumina ILMN Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	66.2%+0.1pp	66.1%-0.1pp	66.2%-0.3pp	66.6%+0.2pp	66.3%+0.9pp
Operating margin	19.4%+0.8pp	18.6%—	——	——	——
Net margin	19.4%-0.2pp	19.6%+3.2pp	16.4%-13.0pp	29.3%+51.6pp	-22.3%+5.7pp
Returns
Return on equity	33.8%+0.5pp	33.4%+2.2pp	31.2%-36.9pp	68.1%+91.9pp	-23.8%+6.3pp
Return on invested capital	19.6%+0.8pp	18.8%—	——	——	——
Efficiency
Asset turnover	0.7×0.0×	0.7×0.0×	0.7×0.0×	0.7×+0.2×	0.5×0.0×
Liquidity
Current ratio	1.7×-0.3×	2.1×+0.6×	1.4×-0.4×	1.8×0.0×	1.9×+0.1×
Leverage
Debt-to-equity	0.8×0.0×	0.8×+0.1×	0.7×-0.3×	0.9×0.0×	0.9×0.0×
Net debt / EBITDA	0.9×+0.3×	0.6×—	——	——	——
Per Share
Book value per share	$17.38-0.4%	$17.46+12.9%	$15.46+7.5%	$14.38-3.4%	$14.89-0.2%
Valuation
Market capitalization	$18.85B-6.0%	$20.04B+37.3%	$14.6B+0.8%	$14.49B+15.3%	$12.57B-40.7%
Price / earnings	22.1×-1.5×	23.6×+2.8×	20.8×+9.3×	11.5×—	——
Price / sales	4.3×-0.3×	4.6×+1.2×	3.4×0.0×	3.4×+0.5×	2.9×-1.9×
Price / book	7×-0.3×	7.4×+1.2×	6.1×-0.3×	6.4×+1.1×	5.3×-3.6×
EV / EBITDA	17.7×-1.6×	19.2×—	——	——	——

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Questions, answered.

What are Illumina's profit margins?: Illumina (ILMN) runs a 66.2% gross margin and a 19.4% operating margin, with a 19.4% net margin.
Where do Illumina's ratios come from?: Every ratio is computed from Illumina's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.