What are Insmed's profit margins?

Insmed (INSM) runs a 81.8% gross margin and a -140.6% operating margin, with a -144.4% net margin.

Where do Insmed's ratios come from?

Every ratio is computed from Insmed's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Insmed INSM Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	81.8%+2.1pp	79.7%+3.2pp	76.5%+0.8pp	75.7%-0.8pp	76.5%+0.1pp
Operating margin	-140.6%+65.0pp	-205.6%+53.3pp	-258.9%-6.5pp	-252.4%+5.0pp	-257.4%-16.0pp
Net margin	-144.4%+66.1pp	-210.5%+54.3pp	-264.8%-5.0pp	-259.8%+6.1pp	-265.9%-14.7pp
Returns
Return on equity	-294.5%-45.2pp	-249.3%-83.6pp	-165.7%-5.1pp	-160.5%—	——
Return on invested capital	-149.4%-2.8pp	-146.6%-41.8pp	-104.8%+260pp	-365.2%-167pp	-198.3%-60.2pp
Efficiency
Asset turnover	0.4×+0.1×	0.3×+0.1×	0.2×0.0×	0.2×-0.1×	0.3×0.0×
Liquidity
Current ratio	4.5×+0.6×	3.8×-0.8×	4.6×-2.0×	6.7×+0.8×	5.9×+0.4×
Leverage
Debt-to-equity	0.8×0.0×	0.8×+0.2×	0.6×+0.1×	0.5×-11.1×	11.5×+7.5×
Per Share
Book value per share	$3.27-11.9%	$3.71-16.8%	$4.47-32.4%	$6.60+1,104%	$0.55-68.5%
Valuation
Market capitalization	$35.25B-5.0%	$37.12B+21.9%	$30.44B+51.3%	$20.12B+45.7%	$13.81B+11.8%
Price / sales	43×-18.2×	61.2×-6.9×	68.1×+17.6×	50.5×+14.3×	36.2×+2.3×
Price / book	50×-0.2×	50.2×+18.0×	32.2×+16.1×	16.1×-123×	139.3×+96.0×

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Questions, answered.

What are Insmed's profit margins?: Insmed (INSM) runs a 81.8% gross margin and a -140.6% operating margin, with a -144.4% net margin.
Where do Insmed's ratios come from?: Every ratio is computed from Insmed's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.