What are Insmed's profit margins?

Insmed (INSM) runs a 81.8% gross margin and a -140.6% operating margin, with a -144.4% net margin.

Where do Insmed's ratios come from?

Every ratio is computed from Insmed's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Insmed INSM Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	313.8%+5.3pp	308.5%+3.3pp	305.2%-0.7pp	305.9%-1.9pp	307.8%-1.6pp
Operating margin	-857.5%+117pp	-974.4%+35.9pp	-1,010.2%-18.0pp	-992.2%-21.0pp	-971.2%-33.3pp
Net margin	-879.6%+121pp	-1,001.1%+40.7pp	-1,041.8%-12.8pp	-1,029%-15.5pp	-1,013.4%-29.2pp
Returns
Return on equity	-870%—	——	——	——	——
Return on invested capital	-766%+48.9pp	-814.9%-8.5pp	-806.4%+9.7pp	-816.1%-10.2pp	-805.9%+242pp
Efficiency
Asset turnover	1.1×+0.2×	0.9×+0.1×	0.9×0.0×	0.9×0.0×	0.9×0.0×
Liquidity
Current ratio	19.6×-1.4×	21×-1.6×	22.6×-1.7×	24.4×+4.0×	20.4×+4.1×
Leverage
Debt-to-equity	2.7×-10.7×	13.4×-3.2×	16.6×-1.5×	18.1×-30.9×	49×—
Per Share
Book value per share	$18.05+17.8%	$15.33+14.8%	$13.36+14.4%	$11.67+119%	$5.32+224%
Valuation
Market capitalization	$122.92B+21.1%	$101.48B+32.3%	$76.72B+33.3%	$57.57B+21.5%	$47.4B+26.3%
Price / sales	222.8×+6.8×	216.1×+27.2×	188.8×+35.2×	153.7×+20.3×	133.4×+23.8×
Price / book	148.5×-89.2×	237.8×+6.9×	230.8×+8.8×	222×-240×	462.1×—

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Questions, answered.

What are Insmed's profit margins?: Insmed (INSM) runs a 81.8% gross margin and a -140.6% operating margin, with a -144.4% net margin.
Where do Insmed's ratios come from?: Every ratio is computed from Insmed's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.