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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
Profitability
Gross margin36.7%+5.4pp31.3%+1.5pp29.9%-0.3pp30.2%-2.4pp32.6%-1.6pp
Operating margin-127.2%+25.9pp-153.1%+13.2pp-166.3%+3.7pp-170%+17.5pp-187.5%+53.4pp
Net margin-123.9%+24.5pp-148.4%+10.4pp-158.8%+2.7pp-161.4%+15.1pp-176.5%+50.3pp
Returns
Return on equity-47.5%+8.0pp-55.5%-1.6pp-53.9%-0.7pp-53.2%-1.3pp-51.8%+5.6pp
Return on invested capital-59.5%+5.7pp-65.2%0.0pp-65.2%+1.4pp-66.6%-4.2pp-62.4%+7.5pp
Efficiency
Asset turnover0.3×0.0×0.3×0.0×0.3×0.0×0.3×0.0×0.2×0.0×
Liquidity
Current ratio3.6×+0.4×3.2×-0.2×3.4×+0.1×3.3×-0.9×4.2×+0.4×
Leverage
Debt-to-equity0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×
Valuation
Market capitalization$1.45B+33.4%$1.08B+38.0%$785.22M+25.1%$627.8M-42.5%$1.09B-51.6%
Price / sales5.1×+1.0×4.1×+1.0×3.1×+0.5×2.6×-2.5×5.1×-8.6×
Price / book+0.5×1.6×+0.4×1.1×+0.2×0.9×-0.5×1.4×-1.8×

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Questions, answered.

What are Iovance Biotherapeutics, Inc.'s profit margins?
Iovance Biotherapeutics, Inc. (IOVA) runs a 36.7% gross margin and a -127.2% operating margin, with a -123.9% net margin.
Where do Iovance Biotherapeutics, Inc.'s ratios come from?
Every ratio is computed from Iovance Biotherapeutics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.