Skip to content
TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
$669.71M+13.5%$672.71M+20.1%$630.08M+20.6%$609.64M+26.7%$590.17M+33.4%
$771.23M+12.5%$750.23M+7.5%$734.85M+9.6%$688.75M+4.8%$685.51M+3.7%
$349.2M+5.9%$348.2M+8.5%$342.15M+8.2%$335.88M+8.1%$329.84M+5.9%
-$561.06M-9.2%-$535.06M+0.2%-$544.08M-1.6%-$505.18M+7.9%-$513.65M+11.5%
-83.8%+3.3pp-79.5%+16.2pp-86.4%+16.1pp-82.9%+31.2pp-87%+44.1pp
$24.17M-31.3%$25.17M-32.0%$28.7M-19.9%$33.57M+8.4%$35.18M+19.1%
-$605.23M-10.7%-$571.23M-0.7%-$576.36M-2.6%-$530.04M+9.8%-$546.77M+11.2%
$3.69M+45.0%$3.69M+84.5%$3.2M+242%$2.63M+238%$2.55M+225%
-$608.92M-10.9%-$574.92M-1.0%-$579.57M-3.6%-$532.67M+9.0%-$549.32M+10.5%
-90.9%+2.2pp-85.5%+16.1pp-92%+15.1pp-87.4%+34.3pp-93.1%+45.7pp
-$6.10-3.9%-$5.83+7.9%-$5.93+7.2%-$5.52+23.5%-$5.87+26.2%
-$6.10-3.9%-$5.83+7.9%-$5.93+7.2%-$5.52+23.5%-$5.87+26.2%
397.4M+7.7%393.1M+10.2%385M+13.3%380.8M+20.5%368.9M+22.8%
397.4M+7.7%393.1M+10.2%385M+13.3%380.8M+20.5%368.9M+22.8%
$110.34M+24.7%$109.34M+42.0%$97.16M+35.6%$90.19M+46.3%$88.47M+76.0%
$1.23B+11.5%$1.21B+10.2%$1.17B+11.0%$1.11B+8.3%$1.1B+7.9%
$68.66M+12.3%$61.66M-2.1%$57.67M-11.1%$59.23M-11.3%$61.15M-7.6%
$669.71M+13.5%$672.71M+20.1%$630.08M+20.6%$609.64M+26.7%$590.17M+33.4%
-$561.06M-9.2%-$535.06M+0.2%-$544.08M-1.6%-$505.18M+7.9%-$513.65M+11.5%
-$527.06M-10.4%-$500.06M0.0%-$508.33M-1.5%-$469.28M+9.0%-$477.5M+13.3%
-$527.06M-10.4%-$500.06M0.0%-$508.33M-1.5%-$469.28M+9.0%-$477.5M+13.3%
-78.7%+2.2pp-74.3%+15.0pp-80.7%+15.2pp-77%+30.2pp-80.9%+43.6pp
-$561.06M-9.2%-$535.06M+0.2%-$544.08M-1.6%-$505.18M+7.9%-$513.65M+11.5%

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Questions, answered.

What are Ultragenyx Pharmaceutical's profit margins?
Gross margin is 97.2% and operating margin is -83.8%, with a -90.9% net margin.
Where does Ultragenyx Pharmaceutical's income statement data come from?
Every line is extracted from Ultragenyx Pharmaceutical's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.