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Net Change in Cash at other companies

Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
-$198.88M-999%
Jazz Pharmaceuticals logo
Jazz PharmaceuticalsJAZZ
$452.4M+182%
Xenon Pharmaceuticals logo
Xenon PharmaceuticalsXENE
$346.7M+1,431%
Praxis Precision Medicines, Inc. logo
Praxis Precision Medicines, Inc.PRAX
$179M+459%
Harmony Biosciences Holdings, Inc. logo
Harmony Biosciences Holdings, Inc.HRMY
-$163.1M-553%
Nurix Therapeutics, Inc. logo
Nurix Therapeutics, Inc.NRIX
-$175.77M-416%

Other financials

Income statement

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Revenue$6.2M-96.1%
Operating income-$53.4M-148%
Net income-$50.0M-144%
EPS (diluted)-$0.79-142%

Balance sheet

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Cash & equivalents$155.7M-43.4%
Total debt$3.4M-42.5%
Total equity$394.9M+12.8%
Total assets$443.3M+8.9%

Cash flow

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Operating cash flow-$60.6M-146%
CapEx$353.0K+132%
Free cash flow-$60.9M-146%

Valuation

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Market cap$1.94B+436%
Enterprise value$1.79B+1,855%
P/S60.4×+58.5×

Profitability

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Operating margin-577.5%-597pp
Net margin-529.2%-556pp
FCF margin36.2%+18.4pp

Returns & leverage

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Return on equity-45.6%-66.1pp
Debt / equity0.0×
Current ratio+0.6×

Where this comes from

Reported directly by Stoke Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect.

The official record: Stoke Therapeutics, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Stoke Therapeutics, Inc.'s net change in cash?
Stoke Therapeutics, Inc. (STOK) reported net change in cash of $74.44M in Q1 2026.
How has Stoke Therapeutics, Inc.'s net change in cash changed year-over-year?
Stoke Therapeutics, Inc.'s net change in cash decreased by 49.3% year-over-year, from $146.83M to $74.44M.
What is the long-term trend for Stoke Therapeutics, Inc.'s net change in cash?
Over 3 years (2021 to 2025), Stoke Therapeutics, Inc.'s net change in cash has grown at a -32.0% compound annual growth rate (CAGR), from -$142.05M to -$44.66M.
What does net change in cash mean?
Total increase or decrease in cash during the period — the sum of operating, investing, financing cash flows plus FX effects.