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Stoke Therapeutics, Inc. STOK MECP2 — Operating Expenses

Other product segments

Zorevunersen
-$19.85M-12.3%
Payroll And Other Personnel Costs Research And Development
-$16.12M-46.4%
Payroll And Other Personnel Costs Sales General And Administrative
-$11.06M
Other Non Program Costs Sales General And Administrative
-$5.16M
Other External Program Costs
-$3.18M-73.8%
ADOA
-$1.86M-54.8%
Other Non Program Costs Research And Development
-$1.68M-19.4%
SYNGAP1
-$745K-118%

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Other financials

Income statement

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Revenue$6.2M-96.1%
Operating income-$53.4M-148%
Net income-$50.0M-144%
EPS (diluted)-$0.79-142%

Balance sheet

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Cash & equivalents$155.7M-43.4%
Total debt$3.4M-42.5%
Total equity$394.9M+12.8%
Total assets$443.3M+8.9%

Cash flow

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Operating cash flow-$60.6M-146%
CapEx$353.0K+132%
Free cash flow-$60.9M-146%

Valuation

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Market cap$2.06B+187%
Enterprise value$1.91B+206%
P/S64.2×+60.6×

Profitability

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Operating margin-577.5%-597pp
Net margin-529.2%-556pp
FCF margin36.2%+18.4pp

Returns & leverage

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Return on equity-45.6%-66.1pp
Debt / equity0.0×
Current ratio+0.6×

Where this comes from

Reported directly by Stoke Therapeutics, Inc. in its filing.

Tagged under the XBRL concept us-gaap:OperatingExpenses.

The source filing: Stoke Therapeutics, Inc.’s 10-Q, filed May 7, 2026.

Filed
May 7, 2026, 4:06 PM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001193125-26-211874
Line itemThree Months Ended March 31, 2026Three Months Ended March 31, 2025
Zorevunersen(1)19,85417,674
ADOA(1)1,8591,201
SYNGAP1(1)745342
MECP2(1)147
Other external program costs3,1781,829
Payroll and other personnel costs - R&D (2)16,11811,012
Payroll and other personnel costs - SG&A (2)11,0578,929
Other non-program costs - R&D (3)1,6801,407

Item 1. Financial Statements.

FAQ

What is Stoke Therapeutics, Inc.'s MECP2 — operating expenses?
Stoke Therapeutics, Inc. (STOK) reported MECP2 — operating expenses of $0 in Q1 2026.
How has Stoke Therapeutics, Inc.'s MECP2 — operating expenses changed year-over-year?
Stoke Therapeutics, Inc.'s MECP2 — operating expenses increased by 100.0% year-over-year, from -$147K to $0.
What is the long-term trend for Stoke Therapeutics, Inc.'s MECP2 — operating expenses?
Over 2 years (2023 to 2025), Stoke Therapeutics, Inc.'s MECP2 — operating expenses has grown at a -80.7% compound annual growth rate (CAGR), from -$991K to $37K.
What does MECP2 — operating expenses mean?
This metric represents the total costs directly attributable to the research, development, and operational activities associated with the MECP2 therapeutic program. It captures the investment required to advance this specific pipeline asset through preclinical and clinical stages, including personnel, laboratory, and external trial costs. Monitoring these expenses provides insight into the capital intensity and resource allocation strategy for this specific drug development candidate.

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