What are Twist Bioscience Corporation's profit margins?

Twist Bioscience Corporation (TWST) runs a 52.1% gross margin and a -33.9% operating margin, with a -19.8% net margin.

Where do Twist Bioscience Corporation's ratios come from?

Every ratio is computed from Twist Bioscience Corporation's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Twist Bioscience Corporation TWST Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q2 '26	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25
Profitability
Gross margin	52.1%+5.4pp	51.6%+7.0pp	50.7%+8.1pp	49.2%+8.7pp	46.7%+8.4pp
Operating margin	-33.9%+24.0pp	-34.4%+28.8pp	-36.2%+34.4pp	-39.3%+40.3pp	-57.9%+16.7pp
Net margin	-19.8%+35.1pp	-19.6%+40.2pp	-20.6%+46.1pp	-23.5%+51.1pp	-55%+14.3pp
Returns
Return on equity	-18.2%+20.1pp	-16.8%+20.9pp	-16.4%+21.7pp	-17.6%+20.8pp	-38.2%-7.8pp
Return on invested capital	-36.4%+19.1pp	-36%+20.2pp	-38.6%+19.8pp	-40.5%+20.2pp	-55.4%-8.5pp
Efficiency
Asset turnover	0.6×+0.1×	0.6×+0.1×	0.6×+0.1×	0.6×+0.2×	0.5×+0.2×
Liquidity
Current ratio	2.7×-1.8×	3.8×-1.2×	3.6×-1.2×	3.9×-1.0×	4.5×-1.0×
Leverage
Debt-to-equity	0.2×0.0×	0.2×0.0×	0.2×0.0×	0.2×0.0×	0.2×+0.1×
Per Share
Book value per share	$7.380.0%	$7.47-3.1%	$7.91-2.9%	$7.82-7.4%	$7.38-23.9%
Valuation
Market capitalization	$2.91B+24.4%	$1.94B-29.7%	$1.7B-35.3%	$2.15B-24.6%	$2.34B+18.7%
Price / sales	7.1×+0.4×	5×-3.4×	4.5×-3.9×	5.9×-3.7×	6.7×-0.4×
Price / book	6.4×+1.1×	4.3×-1.8×	3.6×-2.0×	4.5×-1.3×	5.3×+1.8×

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Questions, answered.

What are Twist Bioscience Corporation's profit margins?: Twist Bioscience Corporation (TWST) runs a 52.1% gross margin and a -33.9% operating margin, with a -19.8% net margin.
Where do Twist Bioscience Corporation's ratios come from?: Every ratio is computed from Twist Bioscience Corporation's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.