What are Vertex Pharmaceuticals's profit margins?

Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.

Where do Vertex Pharmaceuticals's ratios come from?

Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Vertex Pharmaceuticals VRTX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY

Simplified Detailed

	FY'25	FY'24	FY'23	FY'22
Profitability
Gross margin	344.7%-0.9pp	345.5%-5.4pp	351%-1.0pp	352%0.0pp
EBITDA margin	106.5%+64.5pp	42.1%-129pp	171.4%-17.0pp	188.4%+26.6pp
Free cash flow margin	29.7%+56.2pp	-26.5%-187pp	160.4%—	——
Returns
Return on invested capital	71.8%+44.5pp	27.3%-91.2pp	118.5%-23.9pp	142.4%+12.6pp
Efficiency
Asset turnover	2×0.0×	2×-0.1×	2.1×-0.3×	2.4×0.0×
Inventory turnover	5.1×-2.0×	7.1×-2.1×	9.2×-2.3×	11.4×-0.5×
Liquidity
Current ratio	10.4×-0.8×	11.2×-5.3×	16.5×-2.3×	18.8×+0.7×
Quick ratio	8.9×-1.2×	10.1×-5.6×	15.7×-2.4×	18.2×+0.7×
Cash ratio	4.9×-1.4×	6.3×-0.1×	6.4×+1.1×	5.3×-0.2×
Leverage
Debt-to-equity	0.4×+0.1×	0.3×+0.1×	0.2×-0.1×	0.3×-0.1×
Debt-to-assets	0.3×+0.1×	0.2×+0.1×	0.2×-0.1×	0.2×-0.1×
Interest coverage	845×+767×	78×-254×	332.1×—	——
Per Share
Book value per share	$269.49+7.0%	$251.79+2.5%	$245.71+27.8%	$192.33+32.6%
Valuation
Market capitalization	$455.56B+0.6%	$452.7B+23.5%	$366.56B+27.8%	$286.89B+38.0%
Enterprise value	$442.91B+2.0%	$434.3B+25.0%	$347.55B+25.5%	$277.03B+38.0%
Price / sales	39.5×-3.5×	43×+4.7×	38.3×+4.5×	33.8×+3.8×
Price / book	26.2×-1.8×	28×+5.1×	22.9×-0.3×	23.2×+1.1×
EV / sales	38.4×-2.8×	41.2×+4.9×	36.3×+3.7×	32.7×+3.7×
Free cash flow yield	3.8%+6.4pp	-2.6%-19.5pp	16.9%—	——

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Questions, answered.

What are Vertex Pharmaceuticals's profit margins?: Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.
Where do Vertex Pharmaceuticals's ratios come from?: Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.