What are Xeris Biopharma Holdings, Inc.'s profit margins?

Xeris Biopharma Holdings, Inc. (XERS) runs a 85.9% gross margin and a 11.4% operating margin, with a 3.8% net margin.

Where do Xeris Biopharma Holdings, Inc.'s ratios come from?

Every ratio is computed from Xeris Biopharma Holdings, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Xeris Biopharma Holdings, Inc. XERS Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	85.9%+0.5pp	85.4%+0.9pp	84.6%+2.3pp	82.2%0.0pp	82.2%+0.3pp
Operating margin	11.4%+2.9pp	8.5%+5.5pp	3.1%+7.7pp	-4.7%+6.2pp	-10.9%+6.5pp
Net margin	3.8%+3.6pp	0.2%+6.1pp	-5.9%+7.1pp	-13%+7.2pp	-20.3%+6.7pp
Returns
Return on invested capital	21.4%+6.4pp	15%+10.4pp	4.7%+10.9pp	-6.2%+6.8pp	-13%+8.7pp
Efficiency
Asset turnover	0.9×+0.1×	0.8×+0.1×	0.8×0.0×	0.7×+0.1×	0.7×+0.1×
Liquidity
Current ratio	2.1×-0.1×	2.2×+0.3×	1.9×0.0×	1.9×+0.2×	1.7×+0.1×
Leverage
Debt-to-equity	19.9×+1.0×	18.9×—	——	——	——
Net debt / EBITDA	3.9×-1.7×	5.6×-12.0×	17.6×—	——	——
Per Share
Book value per share	$0.07-7.6%	$0.08+1,750%	-$0.00+96.0%	-$0.12+47.4%	-$0.23-14.2%
Valuation
Market capitalization	$1.28B+76.9%	$1.3B-0.9%	$1.31B+76.1%	$746.32M-11.7%	$845.13M+67.2%
Price / earnings	106.4×—	2,351.1×—	——	——	——
Price / sales	4.1×+0.8×	4.5×-0.5×	4.9×+1.9×	3×-0.8×	3.8×+1.3×
Price / book	98.2×—	95.1×—	——	——	——
EV / EBITDA	38.3×—	55.3×-102×	157.3×—	——	——

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Questions, answered.

What are Xeris Biopharma Holdings, Inc.'s profit margins?: Xeris Biopharma Holdings, Inc. (XERS) runs a 85.9% gross margin and a 11.4% operating margin, with a 3.8% net margin.
Where do Xeris Biopharma Holdings, Inc.'s ratios come from?: Every ratio is computed from Xeris Biopharma Holdings, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.