What are Alnylam Pharmaceuticals's profit margins?

Alnylam Pharmaceuticals (ALNY) runs a 81.0% gross margin and a 17.5% operating margin, with a 11.7% net margin.

Where do Alnylam Pharmaceuticals's ratios come from?

Every ratio is computed from Alnylam Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Alnylam Pharmaceuticals ALNY Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	330.7%-5.3pp	336%-4.6pp	340.6%-2.8pp	343.4%-4.5pp	347.8%+0.3pp
Operating margin	32%+22.5pp	9.5%+21.4pp	-11.9%+17.2pp	-29.1%-11.7pp	-17.4%+3.9pp
Net margin	10.4%+21.5pp	-11.1%+19.9pp	-31%+18.4pp	-49.4%-8.3pp	-41.2%+6.8pp
EBITDA margin	38.8%+21.3pp	17.5%+20.4pp	-2.8%+16.3pp	-19.1%-11.8pp	-7.4%+3.6pp
Free cash flow margin	32.3%+18.3pp	14%+14.4pp	-0.4%—	——	——
Returns
Return on assets	12.1%+16.5pp	-4.4%+12.9pp	-17.3%+10.1pp	-27.4%-4.6pp	-22.9%+3.5pp
Efficiency
Asset turnover	3×+0.3×	2.7×+0.2×	2.4×+0.2×	2.2×-0.1×	2.3×0.0×
Inventory turnover	31.2×+6.9×	24.3×+4.7×	19.6×+3.6×	16×+2.1×	13.9×+1.5×
Liquidity
Current ratio	11.2×+0.1×	11.1×0.0×	11.2×-0.2×	11.4×-0.2×	11.6×-0.1×
Quick ratio	11×+0.1×	10.9×0.0×	10.9×-0.2×	11.1×-0.2×	11.3×-0.1×
Cash ratio	4.2×+0.3×	3.9×+0.3×	3.6×+0.1×	3.5×-0.1×	3.6×+0.2×
Leverage
Debt-to-equity	2.8×-0.4×	3.2×-3.7×	6.9×-7.5×	14.4×—	——
Debt-to-assets	0.2×0.0×	0.2×0.0×	0.2×0.0×	0.3×0.0×	0.3×0.0×
Interest coverage	6.2×+4.1×	2.1×+3.7×	-1.5×+2.9×	-4.4×-1.8×	-2.6×+0.7×
Per Share
Book value per share	$17.26+35.2%	$12.77+71.8%	$7.43+24.3%	$5.98+48.1%	$4.04+510%
Valuation
Market capitalization	$198.56B+4.7%	$189.63B+13.2%	$167.45B+17.1%	$142.98B+8.9%	$131.34B+14.0%
Enterprise value	$193.66B+4.4%	$185.43B+13.1%	$163.93B+17.2%	$139.87B+8.9%	$128.39B+14.0%
Price / sales	60.2×-4.6×	64.9×+0.6×	64.2×+1.8×	62.5×+4.1×	58.3×+5.5×
Price / book	532×-41.2×	573.2×-386×	959.1×-836×	1,794.8×—	——
EV / sales	58.8×-4.7×	63.4×+0.6×	62.9×+1.8×	61.1×+4.1×	57×+5.4×
Free cash flow yield	2.6%+1.7pp	0.9%+1.0pp	-0.1%—	——	——
Earnings yield	1.2%+1.8pp	-0.7%+1.4pp	-2.1%+1.1pp	-3.2%-0.4pp	-2.8%+1.1pp

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Questions, answered.

What are Alnylam Pharmaceuticals's profit margins?: Alnylam Pharmaceuticals (ALNY) runs a 81.0% gross margin and a 17.5% operating margin, with a 11.7% net margin.
Where do Alnylam Pharmaceuticals's ratios come from?: Every ratio is computed from Alnylam Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.