What are Exelixis's profit margins?

Exelixis (EXEL) runs a 96.4% gross margin and a 39.4% operating margin, with a 35.1% net margin.

Where do Exelixis's ratios come from?

Every ratio is computed from Exelixis's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Exelixis EXEL Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	96.4%+0.1pp	96.4%-0.2pp	96.6%0.0pp	96.6%-0.2pp	96.8%+0.3pp
Operating margin	39.4%+1.8pp	37.6%+2.6pp	35%+3.6pp	31.4%-1.8pp	33.1%+5.3pp
Net margin	35.1%+1.4pp	33.7%+4.1pp	29.6%+2.6pp	27%-1.0pp	28%+4.0pp
Returns
Return on equity	41%+5.5pp	35.5%+5.0pp	30.6%+1.6pp	29%-1.2pp	30.2%+7.1pp
Return on invested capital	46.7%+4.4pp	42.3%+4.0pp	38.4%+4.8pp	33.6%-2.7pp	36.2%+9.1pp
Efficiency
Asset turnover	0.9×+0.1×	0.8×0.0×	0.8×0.0×	0.8×0.0×	0.8×+0.1×
Liquidity
Current ratio	3.3×-0.3×	3.6×-0.2×	3.8×+0.2×	3.5×0.0×	3.5×-0.1×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Net debt / EBITDA	-0.1×+0.3×	-0.3×-0.1×	-0.2×-0.3×	0×0.0×	0×0.0×
Per Share
Book value per share	$7.24-5.6%	$7.67-1.2%	$7.76+8.5%	$7.15-3.3%	$7.39-2.4%
Valuation
Market capitalization	$11.29B+1.8%	$11.09B+6.5%	$10.41B+6.8%	$9.75B-4.9%	$10.25B+8.3%
Price / earnings	13.6×-0.6×	14.2×-1.2×	15.4×-0.8×	16.2×+0.3×	15.9×-2.2×
Price / sales	4.8×0.0×	4.8×+0.2×	4.5×+0.2×	4.4×-0.1×	4.5×+0.1×
Price / book	5.8×+0.7×	5.1×+0.3×	4.8×0.0×	4.8×0.0×	4.8×+0.6×
EV / EBITDA	11.6×-0.4×	12×-0.3×	12.3×-1.1×	13.4×+0.4×	13×-2.0×

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Questions, answered.

What are Exelixis's profit margins?: Exelixis (EXEL) runs a 96.4% gross margin and a 39.4% operating margin, with a 35.1% net margin.
Where do Exelixis's ratios come from?: Every ratio is computed from Exelixis's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.