What are Exelixis's profit margins?

Exelixis (EXEL) runs a 96.4% gross margin and a 39.4% operating margin, with a 35.1% net margin.

Where do Exelixis's ratios come from?

Every ratio is computed from Exelixis's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Exelixis EXEL Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	96.4%-0.3pp	96.4%-0.1pp	96.6%+0.4pp	96.6%+0.5pp	96.8%+1.1pp
Operating margin	39.4%+6.3pp	37.6%+9.7pp	35%+9.8pp	31.4%—	33.1%—
Net margin	35.1%+7.1pp	33.7%+9.7pp	29.6%+7.2pp	27%—	28%—
Returns
Return on equity	41%+10.8pp	35.5%+12.4pp	30.6%+10.4pp	29%—	30.2%—
Return on invested capital	46.7%+10.4pp	42.3%+15.2pp	38.4%+14.3pp	33.6%—	36.2%—
Efficiency
Asset turnover	0.9×+0.1×	0.8×+0.1×	0.8×+0.1×	0.8×+0.1×	0.8×+0.2×
Liquidity
Current ratio	3.3×-0.2×	3.6×-0.1×	3.8×-0.2×	3.5×-0.8×	3.5×0.0×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Net debt / EBITDA	-0.1×-0.1×	-0.3×-0.3×	-0.2×-0.1×	0×—	0×—
Per Share
Book value per share	$7.24-2.1%	$7.67+1.2%	$7.76-0.6%	$7.15-0.8%	$7.39+6.2%
Valuation
Market capitalization	$11.29B+10.1%	$11.09B+17.1%	$10.41B+9.8%	$9.75B+42.7%	$10.25B+48.3%
Price / earnings	13.6×-2.4×	14.2×-4.0×	15.4×-4.9×	16.2×—	15.9×—
Price / sales	4.8×+0.3×	4.8×+0.4×	4.5×0.0×	4.4×+1.0×	4.5×+0.7×
Price / book	5.8×+1.0×	5.1×+0.9×	4.8×+0.7×	4.8×+1.6×	4.8×+1.6×
EV / EBITDA	11.6×-1.3×	12×-3.0×	12.3×-4.8×	13.4×—	13×—

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Questions, answered.

What are Exelixis's profit margins?: Exelixis (EXEL) runs a 96.4% gross margin and a 39.4% operating margin, with a 35.1% net margin.
Where do Exelixis's ratios come from?: Every ratio is computed from Exelixis's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.