What is Stoke Therapeutics, Inc.'s return on invested capital?

Stoke Therapeutics, Inc. (STOK) reported return on invested capital of -114.4% in Q1 2026.

What does return on invested capital mean?

Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.

Stoke Therapeutics, Inc. STOK Return on invested capital

Return on invested capital at other companies

Ionis PharmaceuticalsIONS

-51%-21.2pp

Jazz PharmaceuticalsJAZZ

-6.1%-14.2pp

Xenon PharmaceuticalsXENE

-59.1%+48.1pp

Praxis Precision Medicines, Inc.PRAX

-62.2%-21.5pp

Harmony Biosciences Holdings, Inc.HRMY

31.2%-7.3pp

Nurix Therapeutics, Inc.NRIX

-70.2%-7.5pp

Other financials

Income statement

See full

Revenue$6.2M-96.1%

Operating income-$53.4M-148%

Net income-$50.0M-144%

EPS (diluted)-$0.79-142%

Balance sheet

See full

Cash & equivalents$155.7M-43.4%

Total debt$3.4M-42.5%

Total equity$394.9M+12.8%

Total assets$443.3M+8.9%

Cash flow

See full

Operating cash flow-$60.6M-146%

CapEx$353.0K+132%

Free cash flow-$60.9M-146%

Valuation

See full

Market cap$1.94B+436%

Enterprise value$1.79B+1,855%

P/S60.4×+58.5×

Profitability

See full

Operating margin-577.5%-597pp

Net margin-529.2%-556pp

FCF margin36.2%+18.4pp

Returns & leverage

See full

Return on equity-45.6%-66.1pp

Debt / equity0×0.0×

Current ratio9×+0.6×

Where this comes from

Calculated from Stoke Therapeutics, Inc.’s reported figures.

nopat/invested capital=-114.4%

Based on trailing twelve months.

The official record: Stoke Therapeutics, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

Ask your AI about Stoke Therapeutics, Inc.'s return on invested capital.

Connect your AI assistant and compare it to peers, right in your chat.

Connect your AI

Claude

Questions, answered.

What is Stoke Therapeutics, Inc.'s return on invested capital?: Stoke Therapeutics, Inc. (STOK) reported return on invested capital of -114.4% in Q1 2026.
What does return on invested capital mean?: Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.