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Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
Returns
Return on equity-31.1%+34.7pp-25.2%+34.1pp-38.1%-49.8%-65.8%+326pp
Liquidity
Current ratio+0.9×13.3×+2.0×10.9×+3.6×6.5×-13.2×8.1×-3.3×
Per Share
Book value per share$8.54+6.6%$11.17+1.4%$7.53+17.1%$7.55-8.6%$8.01+92.0%
Valuation
Market capitalization$3.96B+307%$2.54B+82.6%$1.01B-32.4%$930.05M-22.1%$972.25M-29.1%
Price / book5.9×+3.9×3.6×+0.9×2.2×-2.3×-1.1×-7.0×

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Questions, answered.

Where do Spyre Therapeutics, Inc.'s ratios come from?
Every ratio is computed from Spyre Therapeutics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.