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Price / book at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
5.3×-0.2×
Eli Lilly logo
Eli LillyLLY
31.6×-6.7×
Pfizer logo
PfizerPFE
1.8×+0.2×
Johnson & Johnson logo
Johnson & JohnsonJNJ
7.2×+2.5×
Merck & Co. logo
Merck & Co.MRK
6.5×+1.8×
AbbVie logo
AbbVieABBV
261×+221×

Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$9.2B+854%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Calculated from Spyre Therapeutics, Inc.’s reported figures.

Based on the most recent quarter.

The source filing: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026. Open the filing →

Filed
May 5, 2026, 8:00 AM EDT
Fiscal quarter
Q1 FY2026
Calendar quarter
Q1 2026
Accession
0001636282-26-000050

FAQ

What is Spyre Therapeutics, Inc.'s price / book?
Spyre Therapeutics, Inc. (SYRE) reported price / book of 5.9× in Q1 2026.
How has Spyre Therapeutics, Inc.'s price / book changed year-over-year?
Spyre Therapeutics, Inc.'s price / book increased by 193.1% year-over-year, from 2× to 5.9×.
What is the long-term trend for Spyre Therapeutics, Inc.'s price / book?
Over 5 years (2020 to 2025), Spyre Therapeutics, Inc.'s price / book has grown at a 3.4% compound annual growth rate (CAGR), from 3× to 3.6×.
What does price / book mean?
Market capitalization at the quarter end divided by shareholders' equity. The premium (or discount) the market assigns to the company's book equity.

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