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Spyre Therapeutics, Inc. SYRE Market capitalization

Market capitalization at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
$123.83B-0.2%
Eli Lilly logo
Eli LillyLLY
$821.68B+10.8%
Pfizer logo
PfizerPFE
$159.73B+11.1%
Johnson & Johnson logo
Johnson & JohnsonJNJ
$588.76B+47.3%
Merck & Co. logo
Merck & Co.MRK
$297.4B+31.2%
AbbVie logo
AbbVieABBV
$384.69B+3.8%

Other financials

Income statement

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Revenue-—
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-—
Free cash flow-$39.4M-26.8%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp
FCF margin-3,442.8%-3,807pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio9×+0.9×

Where this comes from

Computed from the period-end share price: $3.96B.

The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s market capitalization?
Spyre Therapeutics, Inc. (SYRE) reported market capitalization of $3.96B in Q1 2026.
How has Spyre Therapeutics, Inc.'s market capitalization changed year-over-year?
Spyre Therapeutics, Inc.'s market capitalization increased by 307.5% year-over-year, from $972.25M to $3.96B.
What is the long-term trend for Spyre Therapeutics, Inc.'s market capitalization?
Over 5 years (2020 to 2025), Spyre Therapeutics, Inc.'s market capitalization has grown at a 43.3% compound annual growth rate (CAGR), from $420.04M to $2.54B.
What does market capitalization mean?
The total market value of the company's equity at the quarter end (share price × shares outstanding), sampled from daily market data. The latest point tracks the live price.