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Spyre Therapeutics, Inc. SYRE Free cash flow margin

Discontinued — last reported Q4 '22

Free cash flow margin at other companies

Bristol-Myers Squibb logo
Bristol-Myers SquibbBMY
24.6%-2.9pp
Eli Lilly logo
Eli LillyLLY
16.4%+8.7pp
Pfizer logo
PfizerPFE
18%+8.8pp
Johnson & Johnson logo
Johnson & JohnsonJNJ
18.5%-4.3pp
Merck & Co. logo
Merck & Co.MRK
21.5%-5.2pp
AbbVie logo
AbbVieABBV
31.8%+5.0pp

Other financials

Income statement

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Revenue-
Operating income-$45.6M+14.8%
Net income-$69.0M-54.1%
EPS (diluted)-$0.74-23.3%

Balance sheet

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Cash & equivalents$97.2M+100%
Total debt$4.3M-9.6%
Total equity$670.8M+39.0%
Total assets$764.0M+34.1%

Cash flow

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Operating cash flow-$57.4M-40.0%
CapEx-
Free cash flow-$39.4M-26.8%

Valuation

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Market cap$7.67B+307%

Profitability

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Operating margin-39,428.9%-49,795pp
Net margin-52,939.7%-61,871pp

Returns & leverage

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Return on equity-31.1%-10.7pp
Debt / equity0.1×+0.1×
Current ratio+0.9×

Where this comes from

Calculated from Spyre Therapeutics, Inc.’s reported figures.

Based on trailing twelve months.

The official record: Spyre Therapeutics, Inc.’s 10-K, filed February 27, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Spyre Therapeutics, Inc.'s free cash flow margin?
Spyre Therapeutics, Inc. (SYRE) reported free cash flow margin of -3,442.8% in Q4 2022.
How has Spyre Therapeutics, Inc.'s free cash flow margin changed year-over-year?
Spyre Therapeutics, Inc.'s free cash flow margin decreased by 1045.1% year-over-year, from -300.7% to -3,442.8%.
What does free cash flow margin mean?
How much real, spendable cash each sales dollar generates after reinvestment.
How do you interpret free cash flow margin?
A high and rising FCF margin is the hallmark of a cash-generative business. Persistent gaps between net margin and FCF margin warrant a look at working capital or capital intensity.
How does free cash flow margin compare across companies?
Strong cross-company quality signal; capital-light compounders post structurally higher FCF margins than asset-heavy peers.