Spyre Therapeutics, Inc. SYRE Return on equity
Return on equity at other companies
Other financials
Where this comes from
Calculated from Spyre Therapeutics, Inc.’s reported figures.
Based on trailing twelve months.
The official record: Spyre Therapeutics, Inc.’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →
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Questions, answered.
- What is Spyre Therapeutics, Inc.'s return on equity?
- Spyre Therapeutics, Inc. (SYRE) reported return on equity of -31.1% in Q1 2026.
- How has Spyre Therapeutics, Inc.'s return on equity changed year-over-year?
- Spyre Therapeutics, Inc.'s return on equity increased by 52.7% year-over-year, from -65.8% to -31.1%.
- What is the long-term trend for Spyre Therapeutics, Inc.'s return on equity?
- Over 5 years (2020 to 2025), Spyre Therapeutics, Inc.'s return on equity has grown at a -20.8% compound annual growth rate (CAGR), from -80.9% to -25.2%.
- What does return on equity mean?
- How much profit the company earns on the money shareholders have invested.
- How do you interpret return on equity?
- Higher is better, but very high ROE can be manufactured by leverage — a thin equity base inflates the ratio. Read it next to debt-to-equity and ROIC to tell genuine returns from balance-sheet engineering.
- How does return on equity compare across companies?
- Comparable across peers, with the leverage caveat. Negative or near-zero equity makes ROE meaningless, so it is suppressed there.