What are Vertex Pharmaceuticals's profit margins?

Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.

Where do Vertex Pharmaceuticals's ratios come from?

Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Vertex Pharmaceuticals VRTX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	86.2%0.0pp	86.2%0.0pp	86.3%+0.2pp	86.1%+0.1pp	86%-0.1pp
Operating margin	38.3%+3.5pp	34.8%—	——	——	——
Net margin	35.5%+2.6pp	32.9%—	——	——	——
EBITDA margin	40.1%+3.6pp	36.5%-0.2pp	36.7%-0.4pp	37.1%+40.9pp	-3.8%-4.6pp
Free cash flow margin	30.4%+3.8pp	26.6%+4.0pp	22.6%+11.1pp	11.5%+42.5pp	-31%-4.0pp
Returns
Return on equity	24.2%+1.7pp	22.5%—	——	——	——
Return on assets	17.6%+1.2pp	16.4%—	——	——	——
Return on invested capital	26.8%+2.5pp	24.3%-1.4pp	25.7%-1.3pp	27%+32.4pp	-5.3%-4.8pp
Efficiency
Asset turnover	0.5×0.0×	0.5×0.0×	0.5×0.0×	0.5×0.0×	0.5×0.0×
Inventory turnover	1.1×-0.1×	1.1×0.0×	1.2×-0.1×	1.3×-0.1×	1.4×-0.1×
Liquidity
Current ratio	3×+0.1×	2.9×+0.5×	2.4×-0.2×	2.5×-0.1×	2.6×0.0×
Quick ratio	2.6×+0.1×	2.5×+0.5×	2×-0.2×	2.2×-0.1×	2.3×-0.1×
Cash ratio	1.4×+0.1×	1.3×+0.2×	1.1×-0.1×	1.2×0.0×	1.2×0.0×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Debt-to-assets	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Net debt / EBITDA	-0.7×0.0×	-0.7×0.0×	-0.7×+0.1×	-0.8×—	——
Per Share
Book value per share	$75.54+4.4%	$72.35+7.6%	$67.23+1.3%	$66.34+4.4%	$63.57-0.1%
Valuation
Market capitalization	$113.44B-1.4%	$115.03B+14.6%	$100.41B-13.2%	$115.63B-7.1%	$124.5B+20.0%
Enterprise value	$109.92B-1.8%	$111.97B+15.1%	$97.3B-13.3%	$112.17B-7.6%	$121.46B+20.4%
Price / earnings	26.1×-2.9×	29.1×—	——	——	——
Price / sales	9.3×-0.3×	9.6×+1.0×	8.6×-1.6×	10.1×-1.1×	11.2×+1.8×
Price / book	5.9×-0.3×	6.2×+0.4×	5.8×-0.9×	6.7×-0.8×	7.5×+1.2×
EV / EBITDA	22.4×-3.1×	25.5×+3.0×	22.6×-3.9×	26.5×—	——
EV / sales	9×-0.3×	9.3×+1.0×	8.3×-1.5×	9.8×-1.1×	10.9×+1.8×
Free cash flow yield	3.3%+0.5pp	2.8%+0.1pp	2.6%+1.5pp	1.1%+3.9pp	-2.8%+0.1pp
Earnings yield	3.8%+0.4pp	3.4%—	——	——	——

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Questions, answered.

What are Vertex Pharmaceuticals's profit margins?: Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.
Where do Vertex Pharmaceuticals's ratios come from?: Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.