| Segment | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| TRIKAFTA/KAFTRIO | $2.45B | $2.59B | $2.72B | $2.54B | $2.55B | $2.65B | $2.57B | $2.35B |
| ALYFTREK | — | — | — | $53.90M | $156.80M | $247.00M | $380.10M | $424.40M |
| Other CF product revenues | — | $186.90M | $191.20M | $170.80M | $236.10M | $175.80M | $237.40M | $135.90M |
| CASGEVY | $0.00 | $2.00M | — | $14.20M | $30.40M | $16.90M | $54.30M | $42.90M |
| JOURNAVX | — | — | — | — | $12.00M | $19.60M | $26.70M | $29.00M |
| Total | $2.65B | $2.77B | $2.91B | $2.77B | $2.96B | $3.08B | $3.19B | $2.99B |