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Vertex Pharmaceuticals VRTX Total CF product revenues, net — Total revenues

Other product segments

TRIKAFTA/KAFTRIO
$2.35B-7.1%
ALYFTREK
$424.4M+687%
Other CF product revenues
$135.9M-12.5%
CASGEVY
$42.9M
JOURNAVX
$29M

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Other financials

Income statement

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Revenue$3.0B+7.8%
Gross profit$2.6B+7.8%
Operating income$1.1B+80.6%
Net income$1.0B+59.6%
EPS (diluted)$4.02+61.4%

Balance sheet

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Cash & equivalents$5.5B+17.5%
Total debt$2.0B+20.5%
Total equity$19.4B+17.4%
Total assets$26.5B+15.8%

Cash flow

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Operating cash flow$1.4B+74.4%
CapEx$133.4M+228%
Free cash flow$1.3B+66.4%

Valuation

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Market cap$114.63B-8.9%
Enterprise value$111.11B-9.5%
P/E26.4×
P/S9.4×-2.0×

Profitability

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Gross margin86.2%+0.2pp
Operating margin38.3%
Net margin35.5%
FCF margin30.4%+20.2pp

Returns & leverage

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Return on equity24.2%
Debt / equity0.1×0.0×
Current ratio+0.4×

Where this comes from

Reported directly by Vertex Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The official record: Vertex Pharmaceuticals’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Vertex Pharmaceuticals's total CF product revenues, net — total revenues?
Vertex Pharmaceuticals (VRTX) reported total CF product revenues, net — total revenues of $2.92B in Q1 2026.
What does total CF product revenues, net — total revenues mean?
This metric represents the aggregate net sales generated from the company's portfolio of cystic fibrosis therapeutic products. It serves as the primary revenue stream for the organization, reflecting the market adoption and commercial success of its core disease-modifying treatments. Monitoring this figure provides insight into the company's ability to maintain its standard-of-care position within the cystic fibrosis market.