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TTM Q1 '26TTM Q4 '25TTM Q3 '25TTM Q2 '25TTM Q1 '25
Profitability
Gross margin330.7%-17.1pp336%-11.5pp340.6%-5.9pp343.4%-2.2pp347.8%+6.7pp
Operating margin32%+49.4pp9.5%+30.8pp-11.9%+17.0pp-29.1%+11.3pp-17.4%+94.2pp
Net margin10.4%+51.6pp-11.1%+36.8pp-31%+28.7pp-49.4%+23.9pp-41.2%+115pp
EBITDA margin38.8%+46.2pp17.5%+28.5pp-2.8%+15.3pp-19.1%+10.1pp-7.4%+91.1pp
Free cash flow margin32.3%14%-0.4%
Returns
Return on assets12.1%+35.0pp-4.4%+21.9pp-17.3%+14.0pp-27.4%+9.5pp-22.9%+43.7pp
Efficiency
Asset turnover+0.7×2.7×+0.4×2.4×+0.2×2.2×+0.1×2.3×+0.4×
Inventory turnover31.2×+17.3×24.3×+12.0×19.6×+8.4×16×+5.8×13.9×+4.5×
Liquidity
Current ratio11.2×-0.3×11.1×-0.6×11.2×-0.9×11.4×-1.0×11.6×-1.0×
Quick ratio11×-0.3×10.9×-0.5×10.9×-0.7×11.1×-0.9×11.3×-0.9×
Cash ratio4.2×+0.6×3.9×+0.5×3.6×+0.2×3.5×-0.1×3.6×+0.1×
Leverage
Debt-to-equity2.8×3.2×6.9×14.4×
Debt-to-assets0.2×0.0×0.2×0.0×0.2×0.0×0.3×0.0×0.3×0.0×
Interest coverage6.2×+8.8×2.1×+5.4×-1.5×+2.8×-4.4×+1.5×-2.6×+10.5×
Per Share
Book value per share$17.26+327%$12.77+1,396%$7.43+327%$5.98+225%$4.04+150%
Valuation
Market capitalization$198.56B+51.2%$189.63B+64.6%$167.45B+53.8%$142.98B+49.4%$131.34B+48.2%
Enterprise value$193.66B+50.8%$185.43B+64.7%$163.93B+54.0%$139.87B+49.8%$128.39B+48.3%
Price / sales60.2×+1.9×64.9×+12.0×64.2×+11.7×62.5×+14.0×58.3×+3.9×
Price / book532×573.2×959.1×1,794.8×
EV / sales58.8×+1.7×63.4×+11.8×62.9×+11.5×61.1×+13.8×57×+3.8×
Free cash flow yield2.6%0.9%-0.1%
Earnings yield1.2%+3.9pp-0.7%+3.2pp-2.1%+2.7pp-3.2%+3.0pp-2.8%+7.6pp

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Questions, answered.

What are Alnylam Pharmaceuticals's profit margins?
Alnylam Pharmaceuticals (ALNY) runs a 81.0% gross margin and a 17.5% operating margin, with a 11.7% net margin.
Where do Alnylam Pharmaceuticals's ratios come from?
Every ratio is computed from Alnylam Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.