What are Castle Biosciences's profit margins?

Castle Biosciences (CSTL) runs a 77.9% gross margin and a -9.8% operating margin, with a -3.8% net margin.

Where do Castle Biosciences's ratios come from?

Every ratio is computed from Castle Biosciences's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Castle Biosciences CSTL Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Gross margin	77.9%-4.1pp	79.4%-2.5pp	79.9%-2.0pp	81%-0.9pp	81.9%+1.4pp
Operating margin	-9.8%-5.8pp	-12.4%-15.0pp	-10.2%-9.8pp	-6.7%-1.2pp	-4%+12.7pp
Net margin	-3.8%-2.3pp	-7%-12.5pp	-3.6%-5.5pp	-2.7%-1.7pp	-1.5%+10.8pp
Returns
Return on equity	-2.8%-1.6pp	-5.2%-9.5pp	-2.7%-4.2pp	-2.2%-1.4pp	-1.2%+6.6pp
Return on invested capital	-8.2%-4.4pp	-11.4%-13.9pp	-8.8%-8.5pp	-6%-1.2pp	-3.8%+9.5pp
Efficiency
Asset turnover	0.6×-0.1×	0.6×-0.1×	0.6×0.0×	0.7×0.0×	0.7×+0.2×
Liquidity
Current ratio	6.7×-2.6×	5.3×-2.0×	6.5×-1.3×	6.9×-1.3×	9.4×+0.1×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×
Per Share
Book value per share	$15.44+0.3%	$16.24+4.3%	$16.06+7.1%	$15.41+4.5%	$15.39+5.1%
Valuation
Market capitalization	$694.86M+29.9%	$1.14B+52.1%	$660.52M-16.5%	$553.19M-8.0%	$570.85M-6.1%
Price / sales	2×+0.5×	3.3×+1.1×	1.9×-0.6×	1.6×-0.5×	1.6×-0.8×
Price / book	1.5×+0.3×	2.4×+0.8×	1.4×-0.4×	1.2×-0.2×	1.3×-0.2×

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Ask your AI about Castle Biosciences.

Connect your AI assistant and get a quick read on the numbers, right in your chat.

Connect your AI

Claude

Questions, answered.

What are Castle Biosciences's profit margins?: Castle Biosciences (CSTL) runs a 77.9% gross margin and a -9.8% operating margin, with a -3.8% net margin.
Where do Castle Biosciences's ratios come from?: Every ratio is computed from Castle Biosciences's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.