How has Denali Therapeutics Inc.'s available for sale investments changed year-over-year?

Denali Therapeutics Inc.'s available for sale investments decreased by 33.4% year-over-year, from $996.82M to $663.84M.

What is the long-term trend for Denali Therapeutics Inc.'s available for sale investments?

Over 5 years (2020 to 2025), Denali Therapeutics Inc.'s available for sale investments has grown at a -5.2% compound annual growth rate (CAGR), from $995.25M to $760.88M.

Denali Therapeutics Inc. DNLI Available for sale investments

Available for sale investments at other companies

Regeneron PharmaceuticalsREGN

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BiogenBIIB

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BridgeBio PharmaBBIO

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BioMarin PharmaceuticalsBMRN

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BioCryst PharmaceuticalsBCRX

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Other financials

Income statement

See full

Revenue-—

Operating income-$137.4M+5.6%

Net income-$128.4M+3.4%

EPS (diluted)-$0.69+11.5%

Balance sheet

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Cash & equivalents$390.7M+551%

Total debt$40.0M-22.3%

Total equity$926.1M-17.5%

Total assets$1.3B-0.4%

Cash flow

See full

Operating cash flow-$131.2M+0.2%

CapEx$2.5M-51.4%

Free cash flow-$133.7M+2.1%

Valuation

See full

Market cap$3.93B+54.2%

Profitability

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Operating margin-37,938%-37,986pp

Net margin-33,121.9%-33,159pp

FCF margin-31,736.3%-31,830pp

Returns & leverage

See full

Return on equity-49.6%+34.2pp

Debt / equity0×0.0×

Current ratio9.3×-0.3×

Where this comes from

Reported directly by Denali Therapeutics Inc. in its filing.

Tagged under the XBRL concept us-gaap:AvailableForSaleSecuritiesDebtSecurities.

The official record: Denali Therapeutics Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Denali Therapeutics Inc.'s available for sale investments?: Denali Therapeutics Inc. (DNLI) reported available for sale investments of $663.84M in Q1 2026.
How has Denali Therapeutics Inc.'s available for sale investments changed year-over-year?: Denali Therapeutics Inc.'s available for sale investments decreased by 33.4% year-over-year, from $996.82M to $663.84M.
What is the long-term trend for Denali Therapeutics Inc.'s available for sale investments?: Over 5 years (2020 to 2025), Denali Therapeutics Inc.'s available for sale investments has grown at a -5.2% compound annual growth rate (CAGR), from $995.25M to $760.88M.