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Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
Profitability
Gross margin36.7%+4.1pp31.3%-2.9pp29.9%+1.2pp30.2%+44.9pp32.6%+368pp
Operating margin-127.2%+60.3pp-153.1%+87.8pp-166.3%+307pp-170%+1,231pp-187.5%+24,362pp
Net margin-123.9%+52.6pp-148.4%+78.5pp-158.8%+292pp-161.4%+1,182pp-176.5%+23,439pp
EBITDA margin-122.6%+59.3pp-148.3%+85.2pp-161.4%+299pp-164.9%+1,200pp-181.9%+23,752pp
Free cash flow margin-106.8%+56.6pp-127.6%+94.3pp-140.5%+271pp-134%+1,088pp-163.4%+21,112pp
Returns
Return on equity-47.5%+4.3pp-55.5%+2.0pp-53.9%+2.8pp-53.2%+12.2pp-51.8%+14.9pp
Return on assets-37.4%+3.5pp-42.9%+1.1pp-41.9%+2.5pp-41.7%+9.5pp-40.9%+12.2pp
Return on invested capital-59.5%+2.9pp-65.2%+4.6pp-65.2%+12.9pp-66.6%+27.3pp-62.4%+49.4pp
Efficiency
Asset turnover0.3×+0.1×0.3×+0.1×0.3×+0.2×0.3×+0.2×0.2×+0.2×
Inventory turnover2.9×-0.5×3.5×0.0×3.9×4.3×3.4×
Liquidity
Current ratio3.6×-0.6×3.2×-0.5×3.4×-0.8×3.3×-1.9×4.2×-0.5×
Quick ratio3.2×-0.5×2.8×-0.5×-0.9×2.9×-2.0×3.6×-0.8×
Cash ratio1.5×+0.1×1.2×+0.2×1.3×-0.2×-1.5×1.4×-0.2×
Leverage
Debt-to-equity0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×0.1×-0.1×
Debt-to-assets0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×0.1×0.0×
Per Share
Book value per share$1.72-27.5%$1.95-20.2%$2.09-22.6%$2.38-6.9%
Valuation
Market capitalization$1.45B+32.4%$1.08B-51.9%$785.22M-70.6%$627.8M-70.6%$1.09B-71.2%
Enterprise value$1.3B+33.2%$969.09M-55.9%$678.58M-73.7%$547.49M-72.4%$972.88M-74.0%
Price / sales5.1×-0.1×4.1×-9.6×3.1×-26.3×2.6×-62.6×5.1×-1,987×
Price / book+0.6×1.6×-1.6×1.1×-2.3×0.9×-1.9×1.4×-4.2×
EV / sales4.5×0.0×3.7×-9.7×2.7×-25.7×2.3×-58.2×4.6×-1,961×
Free cash flow yield-21.1%+10.7pp-31%-14.9pp-44.8%-30.8pp-51.5%-32.8pp-31.8%-21.1pp
Earnings yield-24.5%+9.9pp-36.1%-19.6pp-50.6%-35.3pp-62.1%-41.5pp-34.4%-22.5pp

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Questions, answered.

What are Iovance Biotherapeutics, Inc.'s profit margins?
Iovance Biotherapeutics, Inc. (IOVA) runs a 36.7% gross margin and a -127.2% operating margin, with a -123.9% net margin.
Where do Iovance Biotherapeutics, Inc.'s ratios come from?
Every ratio is computed from Iovance Biotherapeutics, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.