What is Prime Medicine's revenue?

Prime Medicine (PRME) generated $4.6M in revenue over the trailing twelve months, up 55.3% year over year.

Is Prime Medicine profitable?

Prime Medicine is not currently profitable: it reported a net loss of $198.4M over the trailing twelve months, a -4342.4% net margin.

What is Prime Medicine's earnings per share?

Prime Medicine's diluted EPS over the trailing twelve months is $-1.25.

Where does Prime Medicine's income statement data come from?

Every line is extracted from Prime Medicine's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.

Prime Medicine PRME Income Statement

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Total revenue	——	$4.63M+55.3%	$5.98M+647%	$4.96M+739%	$3.85M+551%
Research and development	$154.18M-2.5%	$160.64M+3.4%	$160.03M-1.6%	$156.38M-4.2%	$158.08M+2.1%
General and administrative	$56.47M+8.0%	$52.35M+4.4%	$49.91M-2.0%	$52.8M+11.6%	$52.29M+15.2%
Other operating expenses	$210.65M+0.1%	$212.98M+3.7%	$209.94M-7.6%	$209.18M-6.7%	$210.36M-1.6%
Total operating expenses	$210.65M+0.1%	$212.98M+3.7%	$209.94M-7.6%	$209.18M-6.7%	$210.36M-1.6%
Operating income	-$206.61M0.0%	-$208.35M-2.9%	-$203.96M+9.9%	-$204.22M+8.6%	-$206.52M+3.1%
Interest income	$3.99M-1.0%	$4.15M+17.8%	$4.6M+86.0%	$4.16M+90.1%	$4.03M+82.1%
Other income (expense), net	$8.24M+88.4%	$7.21M+9.5%	$6.63M-5.9%	$4.95M-17.1%	$4.37M-49.5%
Net income	-$198.37M+1.8%	-$201.14M-2.7%	-$197.34M+10.0%	-$199.28M+8.4%	-$202.01M+1.2%
Diluted earnings per share	-$1.25+22.4%	-$1.37+17.0%	-$1.44+30.1%	-$1.56+28.1%	-$1.61+26.1%
Basic earnings per share	-$1.25+22.4%	-$1.37+17.0%	-$1.44+30.1%	-$1.56+28.1%	-$1.61+26.1%
Weighted-average shares, diluted	615.5M+26.0%	569.3M+23.2%	539.2M+24.1%	498.4M+22.6%	488.4M+29.3%
Weighted-average shares, basic	615.5M+26.0%	569.3M+23.2%	539.2M+24.1%	498.4M+22.6%	488.4M+29.3%
Change in fair value of short-term investment — related party	$1.49M—	$432K—	——	——	——
Accretion (Amortization) of Discounts and Premiums, Investments	$2.6M-13.8%	$2.48M-29.3%	$1.93M-55.5%	$2.06M-60.5%	$3.02M-47.0%
Comprehensive Income (Loss), Net of Tax, Attributable to Parent	-$198.36M+1.8%	-$201.06M-2.7%	-$197.33M+9.9%	-$199.21M+8.3%	-$201.93M+1.2%
Unrealized gains (losses) on available-for-sale securities	$14K—	$81K—	——	——	——
Other income, net (Note 6)	$162K+350%	$148K+261%	$142K-2.7%	$15K-94.5%	$36K-86.9%
EBIT	-$206.61M0.0%	-$208.35M-2.9%	-$203.96M+9.9%	-$204.22M+8.6%	-$206.52M+3.1%
EBITDA	-$199.14M+0.4%	-$201.03M-2.4%	-$196.8M+10.8%	-$197.38M+9.5%	-$200.01M+3.9%
EBITDA	-$199.14M+0.4%	-$201.03M-2.4%	-$196.8M+10.8%	-$197.38M+9.5%	-$200.01M+3.9%
EBIT	-$206.61M0.0%	-$208.35M-2.9%	-$203.96M+9.9%	-$204.22M+8.6%	-$206.52M+3.1%

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Questions, answered.

What is Prime Medicine's revenue?: Prime Medicine (PRME) generated $4.6M in revenue over the trailing twelve months, up 55.3% year over year.
Is Prime Medicine profitable?: Prime Medicine is not currently profitable: it reported a net loss of $198.4M over the trailing twelve months, a -4342.4% net margin.
What is Prime Medicine's earnings per share?: Prime Medicine's diluted EPS over the trailing twelve months is $-1.25.
Where does Prime Medicine's income statement data come from?: Every line is extracted from Prime Medicine's SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.