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Prime Medicine PRME Total Operating Expenses

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Segments

By segment

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Reportable Segment$44.44M-18.4%

Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$43.3M+18.9%
Net income-$42.1M+19.9%
EPS (diluted)-$0.24+41.5%

Balance sheet

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Cash & equivalents$61.1M-9.4%
Total debt$112.5M-6.1%
Total equity$39.8M-34.6%
Total assets$249.0M-10.7%

Cash flow

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Operating cash flow-$41.0M+0.9%
CapEx$46.0K-97.1%
Free cash flow-$41.1M+4.4%

Valuation

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Market cap$558.64M-8.7%
Enterprise value$609.98M-8.2%

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%—

Returns & leverage

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Return on equity-373.3%-1,281pp
Debt / equity2.8×+0.9×
Current ratio3.1×-0.5×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:OperatingExpenses.

The source filing: Prime Medicine’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 8:03 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001628280-26-053883
(in thousands, except share and per share amounts)Three Months Ended June 30, 2026Three Months Ended June 30, 2025Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Operating expenses:
Research and development33,39741,37567,50281,937
General and administrative11,04213,11728,44726,401
Total operating expenses44,43954,49295,949108,338
Loss from operations(43,285)(53,377)(93,939)(105,769)
Other income:
Interest income7887431,8091,925
Accretion (amortization) of investments333530793869

Item 1. Financial Statements (unaudited)

FAQ

What is Prime Medicine's total operating expenses?
Prime Medicine (PRME) reported total operating expenses of $44.44M in Q2 2026.
How has Prime Medicine's total operating expenses changed year-over-year?
Prime Medicine's total operating expenses decreased by 18.4% year-over-year, from $54.49M to $44.44M.
What is the long-term trend for Prime Medicine's total operating expenses?
Over 3 years (2022 to 2025), Prime Medicine's total operating expenses has grown at a 22.3% compound annual growth rate (CAGR), from $116.54M to $212.98M.
What does total operating expenses mean?
The sum of all operating costs including COGS, SG&A, R&D, D&A, and other operating charges. Revenue minus total operating expenses equals operating income.

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