What is Xenon Pharmaceuticals's EV / sales?

Xenon Pharmaceuticals (XENE) reported EV / sales of 436.3× in Q4 2025.

What is the long-term trend for Xenon Pharmaceuticals's EV / sales?

Over 3 years (2020 to 2025), Xenon Pharmaceuticals's EV / sales has grown at a 165.3% compound annual growth rate (CAGR), from 23.4× to 436.3×.

What does EV / sales mean?

Enterprise value at the quarter end divided by trailing-twelve-month revenue. A capital-structure-neutral revenue multiple, useful when earnings are negative.

Xenon Pharmaceuticals XENE EV / sales

EV / sales at other companies

Eli LillyLLY

11.9×-4.0×

Johnson & JohnsonJNJ

6.5×+1.8×

Jazz PharmaceuticalsJAZZ

3.7×+1.0×

Axsome TherapeuticsAXSM

12.1×-0.9×

Praxis Precision Medicines, Inc.PRAX

129.5×-403×

Neurocrine BiosciencesNBIX

4.3×-0.4×

Other financials

Income statement

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Revenue--100%

Operating income-$112.3M-54.4%

Net income-$102.3M-57.3%

EPS (diluted)-$1.17-41.0%

Balance sheet

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Cash & equivalents$545.9M+368%

Total debt$7.5M-13.6%

Total equity$1.3B+90.0%

Total assets$1.4B+86.6%

Cash flow

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Operating cash flow-$88.9M-44.2%

CapEx$133.0K+209%

Free cash flow-$89.0M-44.3%

Valuation

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Market cap$5.11B+116%

Profitability

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Operating margin-4,974.3%—

Net margin-4,612.1%—

FCF margin-3,732.2%—

Returns & leverage

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Return on equity-37.5%+8.7pp

Debt / equity0×0.0×

Current ratio27.8×+10.1×

Where this comes from

Calculated from Xenon Pharmaceuticals’s reported figures.

enterprise value/total revenue=436.3×

Based on the most recent quarter.

The official record: Xenon Pharmaceuticals’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Xenon Pharmaceuticals's EV / sales?: Xenon Pharmaceuticals (XENE) reported EV / sales of 436.3× in Q4 2025.
What is the long-term trend for Xenon Pharmaceuticals's EV / sales?: Over 3 years (2020 to 2025), Xenon Pharmaceuticals's EV / sales has grown at a 165.3% compound annual growth rate (CAGR), from 23.4× to 436.3×.
What does EV / sales mean?: Enterprise value at the quarter end divided by trailing-twelve-month revenue. A capital-structure-neutral revenue multiple, useful when earnings are negative.