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Zymeworks ZYME Return on invested capital

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Stoke Therapeutics, Inc.STOK
-114.4%

Other financials

Income statement

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Revenue$2.4M-91.1%
Operating income-$47.1M-84.0%
Net income-$44.2M-95.1%
EPS (diluted)-$0.59-96.7%

Balance sheet

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Cash & equivalents$244.3M+221%
Total debt$17.0M-7.7%
Total equity$163.6M-49.7%
Total assets$478.2M+12.4%

Cash flow

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Operating cash flow-$45.7M-1,242%
CapEx$216.0K+1,250%
Free cash flow-$45.9M-1,242%

Valuation

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Market cap$1.76B+125%
Enterprise value$1.53B+112%
P/S21.6×+13.2×

Profitability

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Operating margin-140.4%+7.3pp
Net margin-126.3%+5.0pp
FCF margin-94.8%+15.5pp

Returns & leverage

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Return on equity-42%+29.2pp
Debt / equity0.1×0.0×
Current ratio10.8×+6.1×

Where this comes from

Calculated from Zymeworks’s reported figures.

Based on trailing twelve months.

The official record: Zymeworks’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Zymeworks's return on invested capital?
Zymeworks (ZYME) reported return on invested capital of -34.5% in Q4 2025.
How has Zymeworks's return on invested capital changed year-over-year?
Zymeworks's return on invested capital increased by 21.4% year-over-year, from -43.9% to -34.5%.
What is the long-term trend for Zymeworks's return on invested capital?
Over 3 years (2022 to 2025), Zymeworks's return on invested capital has grown at a -34.0% compound annual growth rate (CAGR), from 120.1% to -34.5%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.