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Ionis Pharmaceuticals IONS Q1 2026 earnings

Reported April 29, 2026 · Before market open

Revenue$246.0MBeat by $50.4M
EPS-$0.56Beat by $0.29
Revenue estimate$195.6M
EPS estimate-$0.85

Next report

Nov 4, 2026 (in 2 months)
Revenue estimate$181.8M
EPS estimate-$1.22

Financials

Q1 2026

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation & ratios

Valuation

as of 03/31/26
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Market cap$12.4B+159%
Enterprise value$12.92B+175%
P/S11.7×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Segments

By product

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Research And Development Revenue$138.3M+149%
Collaborative Agreement Revenue$120.7M+168%
Commercial$107.8M+41.5%
Royalty$58.3M-9.1%
Spinraza Royalties$43.7M-9.0%

By segment

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Ionis Operations$246.1M+87.0%

FAQ

When did Ionis Pharmaceuticals report Q1 2026 earnings?
Ionis Pharmaceuticals (IONS) reported Q1 2026 earnings on April 29, 2026 before market open.
What were Ionis Pharmaceuticals's Q1 2026 revenue and EPS?
Ionis Pharmaceuticals reported revenue of $246.0M and eps of $-0.56 for Q1 2026.
Did Ionis Pharmaceuticals beat estimates in Q1 2026?
Revenue beat the consensus estimate of $195.6M by $50.4M. EPS beat the consensus estimate of $-0.85 by $0.29.
How did Ionis Pharmaceuticals's Q1 2026 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 86.9% from $131.6M a year earlier and eps grew 25.3% from $-0.75.
Where can I find Ionis Pharmaceuticals's Q1 2026 SEC filings?
You can read the 8-K earnings release (0001140361-26-017637) and the 10-Q periodic report (0000874015-26-000177) directly on SEC EDGAR. The filing index links above go to sec.gov.