Skip to content
Screener

Prime Medicine PRME Net Change in Cash

Net Change in Cash at other companies

Eli Lilly logo
Eli LillyLLY
$3.67B+1,196%
Vertex Pharmaceuticals logo
Vertex PharmaceuticalsVRTX
$417.1M+268%
Intellia Therapeutics logo
Intellia TherapeuticsNTLA
-$28.57M
CRISPR Therapeutics logo
CRISPR TherapeuticsCRSP
$72.24M+215%
Beam Therapeutics logo
Beam TherapeuticsBEAM
-$6.64M-103%
Regenxbio logo
RegenxbioRGNX
$21.26M

Other financials

Income statement

See full
Revenue$838.0K-61.6%
Operating income-$43.3M+18.9%
Net income-$42.1M+19.9%
EPS (diluted)-$0.24+41.5%

Balance sheet

See full
Cash & equivalents$61.1M-9.4%
Total debt$112.5M-6.1%
Total equity$39.8M-34.6%
Total assets$249.0M-10.7%

Cash flow

See full
Operating cash flow-$41.0M+0.9%
CapEx$46.0K-97.1%
Free cash flow-$41.1M+4.4%

Valuation

See full
Market cap$558.64M-8.7%
Enterprise value$609.98M-8.2%

Profitability

See full
Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

See full
Return on equity-373.3%-1,281pp
Debt / equity2.8×+0.9×
Current ratio3.1×-0.5×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect.

The source filing: Prime Medicine’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 8:03 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001628280-26-053883
(in thousands)Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Cash flows provided by financing activities:
Net proceeds from stock option exercises416
Proceeds from ESPP offerings338197
Proceeds from research and development funding liability6,000
Net cash provided by financing activities7546,197
Net change in cash, cash equivalents, and restricted cash(15,581)(129,043)
Cash, cash equivalents, and restricted cash at beginning of period76,723196,538
Cash, cash equivalents, and restricted cash at end of period$61,142$67,495

Item 1. Financial Statements (unaudited)

FAQ

What is Prime Medicine's net change in cash?
Prime Medicine (PRME) reported net change in cash of -$16.66M in Q2 2026.
How has Prime Medicine's net change in cash changed year-over-year?
Prime Medicine's net change in cash increased by 56.7% year-over-year, from -$38.44M to -$16.66M.
What is the long-term trend for Prime Medicine's net change in cash?
Over 2 years (2021 to 2023), Prime Medicine's net change in cash has grown at a -4.9% compound annual growth rate (CAGR), from $161.57M to -$146.05M.
What does net change in cash mean?
Total increase or decrease in cash during the period — the sum of operating, investing, financing cash flows plus FX effects.

Ask your AI about Prime Medicine's net change in cash.

Connect your AI assistant and compare it to peers, right in your chat.

Connect your AI
Harbor at dusk
Claude