What is Prime Medicine's price / book?

Prime Medicine (PRME) reported price / book of 8.2× in Q1 2026.

How has Prime Medicine's price / book changed year-over-year?

Prime Medicine's price / book increased by 235.6% year-over-year, from 2.4× to 8.2×.

What is the long-term trend for Prime Medicine's price / book?

Over 3 years (2022 to 2025), Prime Medicine's price / book has grown at a 5.9% compound annual growth rate (CAGR), from 4.4× to 5.2×.

What does price / book mean?

Market capitalization at the quarter end divided by shareholders' equity. The premium (or discount) the market assigns to the company's book equity.

Prime Medicine PRME Price / book

Price / book at other companies

Eli LillyLLY

26.3×-20.7×

Vertex PharmaceuticalsVRTX

5.9×-1.7×

Intellia TherapeuticsNTLA

2.4×+1.5×

CRISPR TherapeuticsCRSP

2.5×+0.9×

Beam TherapeuticsBEAM

2.1×+0.4×

RegenxbioRGNX

20.5×+19.2×

Other financials

Income statement

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Revenue$838.0K-61.6%

Operating income-$50.7M+3.3%

Net income-$49.1M+5.3%

EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%

Total debt$114.5M-5.5%

Total equity$76.7M-28.3%

Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%

CapEx$214.0K-91.2%

Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%

Enterprise value$611.08M+113%

P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp

Net margin-4,342.4%-1,099pp

FCF margin-3,607.4%—

Returns & leverage

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Return on equity-216.1%+1,519pp

Debt / equity1.5×+0.4×

Current ratio3.8×-1.0×

Where this comes from

Calculated from Prime Medicine’s reported figures.

market cap/total stockholders equity=8.2×

Based on the most recent quarter.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's price / book?: Prime Medicine (PRME) reported price / book of 8.2× in Q1 2026.
How has Prime Medicine's price / book changed year-over-year?: Prime Medicine's price / book increased by 235.6% year-over-year, from 2.4× to 8.2×.
What is the long-term trend for Prime Medicine's price / book?: Over 3 years (2022 to 2025), Prime Medicine's price / book has grown at a 5.9% compound annual growth rate (CAGR), from 4.4× to 5.2×.
What does price / book mean?: Market capitalization at the quarter end divided by shareholders' equity. The premium (or discount) the market assigns to the company's book equity.