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Prime Medicine PRME Business Segments — Net loss

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Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$43.3M+18.9%
Net income-$42.1M+19.9%
EPS (diluted)-$0.24+41.5%

Balance sheet

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Cash & equivalents$61.1M-9.4%
Total debt$112.5M-6.1%
Total equity$39.8M-34.6%
Total assets$249.0M-10.7%

Cash flow

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Operating cash flow-$41.0M+0.9%
CapEx$46.0K-97.1%
Free cash flow-$41.1M+4.4%

Valuation

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Market cap$558.64M-10.7%
Enterprise value$609.98M-10.0%

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Return on equity-373.3%-1,281pp
Debt / equity2.8×+0.9×
Current ratio3.1×-0.5×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:NetIncomeLoss.

The source filing: Prime Medicine’s 10-Q, filed August 6, 2026.

Filed
Aug 6, 2026, 8:03 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001628280-26-053883
(in thousands, except share and per share amounts)Three Months Ended June 30, 2026Three Months Ended June 30, 2025Six Months Ended June 30, 2026Six Months Ended June 30, 2025
Total other income, net1,1767862,7081,288
Net loss attributable to common stockholders$(42,109)$(52,591)$(91,231)$(104,481)
Net loss per share attributable to common stockholders, basic and diluted$(0.24)$(0.41)$(0.51)$(0.81)
Weighted-average common shares outstanding, basic and diluted177,224,892129,185,918177,160,914128,439,349
Comprehensive loss:
Net loss$(42,109)$(52,591)$(91,231)$(104,481)
Change in unrealized (loss) income on investments, net of tax(8)5(91)(11)
Comprehensive loss$(42,117)$(52,586)$(91,322)$(104,492)

Item 1. Financial Statements (unaudited)

FAQ

What is Prime Medicine's business segments — net loss?
Prime Medicine (PRME) reported business segments — net loss of -$42.11M in Q2 2026.
How has Prime Medicine's business segments — net loss changed year-over-year?
Prime Medicine's business segments — net loss increased by 19.9% year-over-year, from -$52.59M to -$42.11M.
What is the long-term trend for Prime Medicine's business segments — net loss?
Over 2 years (2023 to 2025), Prime Medicine's business segments — net loss has grown at a 0.8% compound annual growth rate (CAGR), from -$198.13M to -$201.14M.
What does business segments — net loss mean?
Indicates the bottom-line financial result for a business segment when total operating expenses exceed total revenues. For early-stage biotechnology companies, this metric is a standard measure of the capital required to fund ongoing research and development efforts. It highlights the segment's current reliance on external funding or corporate-level support.

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