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Prime Medicine PRME Business Segments — Net loss

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Other financials

Income statement

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Revenue$838.0K-61.6%
Operating income-$50.7M+3.3%
Net income-$49.1M+5.3%
EPS (diluted)-$0.28+30.0%

Balance sheet

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Cash & equivalents$77.8M-26.6%
Total debt$114.5M-5.5%
Total equity$76.7M-28.3%
Total assets$294.7M-10.2%

Cash flow

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Operating cash flow-$42.7M+12.6%
CapEx$214.0K-91.2%
Free cash flow-$42.9M+16.3%

Valuation

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Market cap$574.36M+111%
Enterprise value$611.08M+113%
P/S124×+6.3×

Profitability

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Operating margin-4,498.1%-1,134pp
Net margin-4,342.4%-1,099pp
FCF margin-3,607.4%

Returns & leverage

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Return on equity-216.1%+1,519pp
Debt / equity1.5×+0.4×
Current ratio3.8×-1.0×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:NetIncomeLoss.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's business segments — net loss?
Prime Medicine (PRME) reported business segments — net loss of -$49.12M in Q1 2026.
How has Prime Medicine's business segments — net loss changed year-over-year?
Prime Medicine's business segments — net loss increased by 5.3% year-over-year, from -$51.89M to -$49.12M.
What is the long-term trend for Prime Medicine's business segments — net loss?
Over 2 years (2023 to 2025), Prime Medicine's business segments — net loss has grown at a 0.8% compound annual growth rate (CAGR), from -$198.13M to -$201.14M.
What does business segments — net loss mean?
Indicates the bottom-line financial result for a business segment when total operating expenses exceed total revenues. For early-stage biotechnology companies, this metric is a standard measure of the capital required to fund ongoing research and development efforts. It highlights the segment's current reliance on external funding or corporate-level support.