What is Prime Medicine's PP&E (net)?

Prime Medicine (PRME) reported PP&E (net) of $18.82M in Q1 2026.

How has Prime Medicine's PP&E (net) changed year-over-year?

Prime Medicine's PP&E (net) decreased by 24.6% year-over-year, from $24.96M to $18.82M.

What is the long-term trend for Prime Medicine's PP&E (net)?

Over 4 years (2021 to 2025), Prime Medicine's PP&E (net) has grown at a 42.9% compound annual growth rate (CAGR), from $4.93M to $20.57M.

What does PP&E (net) mean?

Total property, plant, and equipment minus accumulated depreciation — the net book value of all tangible long-lived assets.

Prime Medicine PRME PP&E (Net)

PP&E (Net) at other companies

Eli LillyLLY

$26.54B+43.7%

Intellia TherapeuticsNTLA

$15.52M-38.2%

CRISPR TherapeuticsCRSP

$112.18M-13.3%

Beam TherapeuticsBEAM

$101.25M-7.6%

RegenxbioRGNX

$101.87M-11.0%

Sarepta Therapeutics, Inc.SRPT

$336.24M-6.8%

Other financials

Income statement

See full

Revenue$838.0K-61.6%

Operating income-$50.7M+3.3%

Net income-$49.1M+5.3%

EPS (diluted)-$0.28+30.0%

Balance sheet

See full

Cash & equivalents$77.8M-26.6%

Total debt$114.5M-5.5%

Total equity$76.7M-28.3%

Total assets$294.7M-10.2%

Cash flow

See full

Operating cash flow-$42.7M+12.6%

CapEx$214.0K-91.2%

Free cash flow-$42.9M+16.3%

Valuation

See full

Market cap$574.36M+111%

Enterprise value$611.08M+113%

P/S124×+6.3×

Profitability

See full

Operating margin-4,498.1%-1,134pp

Net margin-4,342.4%-1,099pp

FCF margin-3,607.4%—

Returns & leverage

See full

Return on equity-216.1%+1,519pp

Debt / equity1.5×+0.4×

Current ratio3.8×-1.0×

Where this comes from

Reported directly by Prime Medicine in its filing.

Tagged under the XBRL concept us-gaap:PropertyPlantAndEquipmentNet.

The official record: Prime Medicine’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Prime Medicine's PP&E (net)?: Prime Medicine (PRME) reported PP&E (net) of $18.82M in Q1 2026.
How has Prime Medicine's PP&E (net) changed year-over-year?: Prime Medicine's PP&E (net) decreased by 24.6% year-over-year, from $24.96M to $18.82M.
What is the long-term trend for Prime Medicine's PP&E (net)?: Over 4 years (2021 to 2025), Prime Medicine's PP&E (net) has grown at a 42.9% compound annual growth rate (CAGR), from $4.93M to $20.57M.
What does PP&E (net) mean?: Total property, plant, and equipment minus accumulated depreciation — the net book value of all tangible long-lived assets.