Where do Protagonist Therapeutics's ratios come from?

Every ratio is computed from Protagonist Therapeutics's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Operating margin	-192.4%+151pp	-343.6%-353pp	9.1%-2.4pp	11.5%-1.6pp	13.1%-45.1pp
Net margin	-154.9%+128pp	-282.8%-305pp	21.9%-2.9pp	24.9%-2.2pp	27%-36.3pp
Returns
Return on equity	-17.1%+3.1pp	-20.2%-28.0pp	7.8%-0.8pp	8.6%-0.4pp	9%-45.4pp
Return on invested capital	-27.6%+1.5pp	-29.1%-32.9pp	3.8%-2.8pp	6.6%+0.9pp	5.6%-61.7pp
Efficiency
Asset turnover	0.1×0.0×	0.1×-0.3×	0.3×0.0×	0.3×0.0×	0.3×-0.5×
Liquidity
Current ratio	17.8×+5.0×	12.7×-0.3×	13×-3.9×	17×-0.3×	17.3×+4.8×
Leverage
Debt-to-equity	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Per Share
Book value per share	$9.30-3.8%	$9.67-4.5%	$10.12-3.8%	$10.52-3.9%	$10.94+5.5%
Valuation
Market capitalization	$6.73B+23.2%	$5.46B+32.1%	$4.13B+24.2%	$3.33B+12.1%	$2.97B+29.0%
Price / sales	90.8×-27.8×	118.7×+98.9×	19.8×+3.8×	15.9×+1.6×	14.3×+9.0×
Price / book	10.3×+1.4×	8.9×+2.5×	6.4×+1.4×	5×+0.7×	4.3×+0.9×

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Where do Protagonist Therapeutics's ratios come from?: Every ratio is computed from Protagonist Therapeutics's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.