Where do Protagonist Therapeutics's ratios come from?

Every ratio is computed from Protagonist Therapeutics's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Profitability
Operating margin	-192.4%—	-343.6%—	9.1%—	——	——
Net margin	-154.9%—	-282.8%—	21.9%—	——	——
Returns
Return on equity	-17.1%—	-20.2%—	7.8%—	——	——
Return on invested capital	-27.6%—	-29.1%—	3.8%—	——	——
Efficiency
Asset turnover	0.1×-0.2×	0.1×-0.7×	0.3×-0.4×	0.3×-0.4×	0.3×-0.4×
Liquidity
Current ratio	17.8×+0.5×	12.7×+0.2×	13×+2.4×	17×+3.2×	17.3×+1.5×
Leverage
Debt-to-equity	0×0.0×	0×0.0×	0×0.0×	0×0.0×	0×0.0×
Per Share
Book value per share	$9.30-15.0%	$9.67-6.8%	$10.12+17.5%	$10.52+19.1%	$10.94+24.2%
Valuation
Market capitalization	$6.73B+127%	$5.46B+137%	$4.13B+49.8%	$3.33B+57.8%	$2.97B+68.6%
Price / sales	90.8×+76.5×	118.7×+113×	19.8×+11.2×	15.9×—	14.3×—
Price / book	10.3×+6.0×	8.9×+5.5×	6.4×+1.2×	5×+1.1×	4.3×+1.2×

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Questions, answered.

Where do Protagonist Therapeutics's ratios come from?: Every ratio is computed from Protagonist Therapeutics's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.