What are Upstream Bio, Inc.'s total assets?

Upstream Bio, Inc. (UPB) holds $318.1M in total assets, down 30.3% year over year.

How much debt does Upstream Bio, Inc. have?

Upstream Bio, Inc. carries $1.1M in total debt against $304.0M of shareholders' equity, a debt-to-equity ratio of 0.00.

How much cash does Upstream Bio, Inc. have?

Upstream Bio, Inc. holds $96.7M in cash and equivalents.

Can Upstream Bio, Inc. cover its short-term obligations?

Its current ratio is 23.14 — current assets exceed current liabilities.

Where does Upstream Bio, Inc.'s balance sheet data come from?

Every line is extracted from Upstream Bio, Inc.'s SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.

Upstream Bio, Inc. UPB Balance Sheet Statement

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	TTM Q1 '26	TTM Q4 '25	TTM Q3 '25	TTM Q2 '25	TTM Q1 '25
Cash and cash equivalents	$96.72M+35.6%	$101.58M-68.8%	$72.16M+119%	$45.46M-4.0%	$71.31M—
Short-term investments	$197.86M—	$239.93M—	$300.26M—	$348.12M—	——
Restricted cash	$194K—	$194K—	$194K—	$194K—	——
Accounts receivable, net	$1.03M—	$668K—	$683K—	$937K—	——
Prepaid expenses and other current assets	$20.67M-5.4%	$9.62M+18.8%	$15.91M+165%	$23.75M—	$21.84M—
Total current assets	$316.28M—	$351.8M—	$389.02M—	$418.27M—	——
Property and equipment, net	$510K—	$559K—	$616K—	$544K—	——
Operating lease right-of-use assets	$1.07M—	$1.22M—	$1.37M—	$1.51M—	——
Total assets	$318.05M—	$353.77M—	$391.2M—	$420.52M—	——
Accounts payable	$1.71M-63.8%	$2.73M-32.5%	$3.95M-19.3%	$2.55M—	$4.72M—
Accrued expenses	$11.24M—	$10.01M—	$7.24M—	$7.67M—	——
Operating lease liabilities, current	$724K—	$720K—	$716K—	$712K—	——
Total current liabilities	$13.67M—	$13.45M—	$11.91M—	$10.93M—	——
Operating lease liabilities, non-current	$390K—	$549K—	$703K—	$849K—	——
Operating Lease Liabilities (Total)	——	——	——	——	——
Total liabilities	$14.06M—	$14M—	$12.61M—	$11.78M—	——
Common stock	$54K—	$54K—	$56K—	$54K—	——
Additional paid-in capital	$678.66M—	$673.41M—	$669.8M—	$666.45M—	——
Retained earnings	-$374.81M—	-$334.22M—	-$291.76M—	-$258.02M—	——
Accumulated other comprehensive income (loss)	$100K—	$530K—	$493K—	$258K—	——
Total stockholders' equity	$304M-31.8%	$339.77M-27.7%	$378.58M+336%	$408.74M+379%	$445.61M+434%
Total liabilities and stockholders' equity	$318.05M—	$353.77M—	$391.2M—	$420.52M—	——
Net Investment in Lease	$1.07M—	$1.22M—	$1.37M—	$1.51M—	——
Operating lease right-of-use assets	$1.07M—	$1.22M—	$1.37M—	$1.51M—	——
Short-term investment securities (includes restricted investments of consolidated variable interest entities: 2026, $85; 2025, $84)	$197.86M—	$239.93M—	$300.26M—	$348.12M—	——
Operating Lease Right-of-Use Assets in Other Assets	$1.07M—	$1.22M—	$1.37M—	$1.51M—	——
Accrued expenses and other liabilities	$11.24M—	$10.01M—	$7.24M—	$7.67M—	——
Total debt	$1.11M—	$1.27M—	$1.42M—	$1.56M—	——
Common stock; $0.001 par value; 6,000 shares authorized; 3,755 and 3,751 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively	$54K—	$54K—	$56K—	$54K—	——

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Ask your AI about Upstream Bio, Inc..

Connect your AI assistant and get a quick read on the numbers, right in your chat.

Connect your AI

Claude

Questions, answered.

What are Upstream Bio, Inc.'s total assets?: Upstream Bio, Inc. (UPB) holds $318.1M in total assets, down 30.3% year over year.
How much debt does Upstream Bio, Inc. have?: Upstream Bio, Inc. carries $1.1M in total debt against $304.0M of shareholders' equity, a debt-to-equity ratio of 0.00.
How much cash does Upstream Bio, Inc. have?: Upstream Bio, Inc. holds $96.7M in cash and equivalents.
Can Upstream Bio, Inc. cover its short-term obligations?: Its current ratio is 23.14 — current assets exceed current liabilities.
Where does Upstream Bio, Inc.'s balance sheet data come from?: Every line is extracted from Upstream Bio, Inc.'s SEC filings (10-K and 10-Q) and tagged in XBRL. Switch between quarterly, annual, and trailing-twelve-month views, or open any line for its full history and peer comparisons.