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Upstream Bio, Inc. UPB Retained Earnings

Retained Earnings at other companies

Amgen logo
AmgenAMGN
-$24.65B+9.2%
Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
$36.42B+12.5%
Aclaris Therapeutics logo
Aclaris TherapeuticsACRS
-$987.61M-7.6%
Shattuck Labs, Inc. logo
Shattuck Labs, Inc.STTK
-$445.3M-12.6%
Savara logo
SavaraSVRA
-$645.37M-25.1%
AnaptysBio, Inc. logo
AnaptysBio, Inc.ANAB
-$825.44M-3.4%

Other financials

Income statement

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Revenue$1.0M+82.7%
Operating income-$43.6M-36.2%
Net income-$40.6M-48.8%
EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%
Total debt$1.1M-34.5%
Total equity$304.0M-31.8%
Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%
CapEx$54.0K-70.8%
Free cash flow-$30.7M-55.0%

Valuation

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Market cap$346.11M-40.9%
Enterprise value$250.5M-51.4%
P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp
Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%
Debt / equity0.0×
Current ratio23.1×-24.3×

Where this comes from

Reported directly by Upstream Bio, Inc. in its filing.

Tagged under the XBRL concept us-gaap:RetainedEarningsAccumulatedDeficit.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s retained earnings?
Upstream Bio, Inc. (UPB) reported retained earnings of -$374.81M in Q1 2026.
How has Upstream Bio, Inc.'s retained earnings changed year-over-year?
Upstream Bio, Inc.'s retained earnings decreased by 71.9% year-over-year, from -$218.05M to -$374.81M.
What is the long-term trend for Upstream Bio, Inc.'s retained earnings?
Over 2 years (2023 to 2025), Upstream Bio, Inc.'s retained earnings has grown at a 61.6% compound annual growth rate (CAGR), from -$127.97M to -$334.22M.
What does retained earnings mean?
Cumulative net income earned since inception minus all dividends paid — the total profits reinvested in the business over its lifetime.