What is Upstream Bio, Inc.'s market capitalization?

Upstream Bio, Inc. (UPB) reported market capitalization of $489.78M in Q1 2026.

How has Upstream Bio, Inc.'s market capitalization changed year-over-year?

Upstream Bio, Inc.'s market capitalization increased by 49.2% year-over-year, from $328.28M to $489.78M.

What does market capitalization mean?

The total market value of the company's equity at the quarter end (share price × shares outstanding), sampled from daily market data. The latest point tracks the live price.

Upstream Bio, Inc. UPB Market capitalization

Market capitalization at other companies

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$189.67B+13.3%

Regeneron PharmaceuticalsREGN

$81.68B+17.8%

Aclaris TherapeuticsACRS

$454.08M+174%

Shattuck Labs, Inc.STTK

$460.16M+911%

SavaraSVRA

$1.12B+134%

AnaptysBio, Inc.ANAB

$1.59B+180%

Other financials

Income statement

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Revenue$1.0M+82.7%

Operating income-$43.6M-36.2%

Net income-$40.6M-48.8%

EPS (diluted)-$0.75-47.1%

Balance sheet

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Cash & equivalents$96.7M+35.6%

Total debt$1.1M-34.5%

Total equity$304.0M-31.8%

Total assets$318.1M-30.3%

Cash flow

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Operating cash flow-$47.9M-16.2%

CapEx$54.0K-70.8%

Free cash flow-$30.7M-55.0%

Valuation

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Enterprise value$250.5M-51.4%

P/S104.2×-151×

Profitability

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Operating margin-5,176.5%+1,764pp

Net margin-4,719%+2,752pp

Returns & leverage

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Return on equity-41.8%—

Debt / equity0×0.0×

Current ratio23.1×-24.3×

Where this comes from

Computed from the period-end share price: $489.78M.

The official record: Upstream Bio, Inc.’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Upstream Bio, Inc.'s market capitalization?: Upstream Bio, Inc. (UPB) reported market capitalization of $489.78M in Q1 2026.
How has Upstream Bio, Inc.'s market capitalization changed year-over-year?: Upstream Bio, Inc.'s market capitalization increased by 49.2% year-over-year, from $328.28M to $489.78M.
What does market capitalization mean?: The total market value of the company's equity at the quarter end (share price × shares outstanding), sampled from daily market data. The latest point tracks the live price.